果蝇生殖系中转座子沉默的诱导

Induction of Transposon Silencing in the Drosophila Germline.

作者信息

Ryazansky S S, Stolyarenko A D, Klenov M S, Gvozdev V A

机构信息

Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia.

出版信息

Biochemistry (Mosc). 2017 May;82(5):565-571. doi: 10.1134/S0006297917050042.

DOI:10.1134/S0006297917050042

PMID:28601066

Abstract

In this review we consider the role of the piRNA system in transposable element silencing in the Drosophila melanogaster germline. We focus on new data that demonstrate the mechanisms of initiation of piRNA biogenesis in ovarian germinal cells and the role of Piwi protein in this process, including our own results.

摘要

在本综述中，我们探讨了piRNA系统在黑腹果蝇生殖系中转座子沉默中的作用。我们重点关注了新的数据，这些数据展示了卵巢生殖细胞中piRNA生物合成起始的机制以及Piwi蛋白在此过程中的作用，包括我们自己的研究结果。