Gerasimov E S, Gasparyan A A, Litus I A, Logacheva M D, Kolesnikov A A
Lomonosov Moscow State University, Faculty of Biology, Moscow, 119991, Russia.
Biochemistry (Mosc). 2017 May;82(5):572-578. doi: 10.1134/S0006297917050054.
We present here the structure of a minicircle population based on transcriptome sequencing of Leptomonas pyrrhocoris. We show that minicircle DNA molecules are dimeric. As in dixenous species, the entire molecule of minicircle DNA is transcribed. This is the first minicircle transcriptome of monoxenous trypanosomatid species determined using NGS technology.
我们在此展示基于梨形利什曼原虫转录组测序的微小环群体结构。我们发现微小环DNA分子是二聚体。与双宿主物种一样，微小环DNA的整个分子都被转录。这是使用NGS技术确定的单宿主锥虫物种的首个微小环转录组。
