Sood Shreya, Hryhorczuk Anastasia L, Rissmiller Julia, Lee Edward Y
Department of Pediatric Radiology, Floating Hospital for Children at Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.
Department of Pediatric Radiology, Floating Hospital for Children at Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.
Radiol Clin North Am. 2017 Jul;55(4):869-893. doi: 10.1016/j.rcl.2017.02.013.
Although pediatric tumors are largely sporadic in cause, continued advancements in science have elucidated a growing body of tumors that are associated with syndromes. Early identification of these syndromic disorders associated with developing tumors can alter the course of disease and potentially save lives. Medical imaging has a pivotal role in screening surveillance, diagnosis, and management of these tumors. Understanding characteristic manifestations of these syndromes is important to optimize image utilization. This article discusses clinically important syndromes associated with pediatric tumors with brief overview of the background, genetics, and clinical features. Diagnosis, imaging, management, and treatment are also reviewed.
尽管儿科肿瘤在病因上大多是散发性的，但科学的不断进步已阐明越来越多与综合征相关的肿瘤。早期识别这些与肿瘤发生相关的综合征性疾病可以改变疾病进程并有可能挽救生命。医学成像在这些肿瘤的筛查监测、诊断和管理中起着关键作用。了解这些综合征的特征性表现对于优化图像利用非常重要。本文讨论了与儿科肿瘤相关的临床重要综合征，并简要概述了其背景、遗传学和临床特征。还对诊断、成像、管理和治疗进行了综述。
