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在急诊科使用“推注剂量”血管加压素的安全性考虑和基于指南的安全使用建议。

Safety Considerations and Guideline-Based Safe Use Recommendations for "Bolus-Dose" Vasopressors in the Emergency Department.

机构信息

Department of Pharmacy, Albany Medical Center, Albany, NY.

Department of Pharmacy, Albany Medical Center, Albany, NY.

出版信息

Ann Emerg Med. 2018 Jan;71(1):83-92. doi: 10.1016/j.annemergmed.2017.04.021.

DOI:10.1016/j.annemergmed.2017.04.021
PMID:28601272
Abstract

The use of intermittently administered doses of vasopressors to correct hypotension in the emergency department (ED), commonly referred to as bolus-dose pressors, push-dose pressors, Neo-sticks, or phenyl sticks, has been widely advocated outside of the traditional printed medical literature. No outcomes data of this practice exist to demonstrate benefits over traditional continuous infusion of vasopressors. Use of bolus-dose vasopressors in the ED setting raises a number of patient safety concerns, and misuse and errors in the preparation and administration of bolus-dose vasopressors may result in patient harm. A systems-based approach should be implemented to maximize safety and patient benefits if bolus-dose vasopressors are used. This article discusses the wide range of issues to consider when evaluating the role of bolus-dose vasopressors in the ED and provides recommendations based on current safe medication practices guidelines.

摘要

在急诊科(ED)中,使用间歇性给予血管加压剂来纠正低血压,通常称为推注剂量加压剂、推注剂量加压剂、Neo-sticks 或苯丙醇棒,这种做法在传统印刷医学文献之外得到了广泛的提倡。目前尚无关于这种做法的结局数据可以证明其优于传统的血管加压剂持续输注。在 ED 环境中使用推注剂量血管加压剂会引起许多患者安全问题,如果使用推注剂量血管加压剂,准备和给药方面的误用和错误可能会导致患者受到伤害。如果使用推注剂量血管加压剂,应采用基于系统的方法来最大限度地提高安全性和患者获益。本文讨论了在评估 ED 中推注剂量血管加压剂作用时需要考虑的广泛问题,并根据当前安全用药实践指南提出了建议。

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