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本文引用的文献

1
Push dose pressors: Experience in critically ill patients outside of the operating room.推注型升压药:在手术室之外的危重症患者中的应用经验。
Am J Emerg Med. 2019 Mar;37(3):494-498. doi: 10.1016/j.ajem.2018.12.001. Epub 2018 Dec 3.
2
Safety Considerations and Guideline-Based Safe Use Recommendations for "Bolus-Dose" Vasopressors in the Emergency Department.在急诊科使用“推注剂量”血管加压素的安全性考虑和基于指南的安全使用建议。
Ann Emerg Med. 2018 Jan;71(1):83-92. doi: 10.1016/j.annemergmed.2017.04.021.
3
Strategies for reducing medication errors in the emergency department.减少急诊科用药错误的策略。
Open Access Emerg Med. 2014 Jul 23;6:45-55. doi: 10.2147/OAEM.S64174. eCollection 2014.
4
Efficacy of Bolus-dose Phenylephrine for Peri-intubation Hypotension.单次剂量去氧肾上腺素治疗气管插管期间低血压的疗效
J Emerg Med. 2015 Oct;49(4):488-94. doi: 10.1016/j.jemermed.2015.04.033. Epub 2015 Jun 20.
5
Nontraumatic hypotension and shock in the emergency department and the prehospital setting, prevalence, etiology, and mortality: a systematic review.急诊科及院前环境中的非创伤性低血压和休克:患病率、病因及死亡率的系统评价
PLoS One. 2015 Mar 19;10(3):e0119331. doi: 10.1371/journal.pone.0119331. eCollection 2015.
6
Vasopressors for the treatment of maternal hypotension following spinal anaesthesia for elective caesarean section: past, present and future.用于择期剖宫产脊髓麻醉后治疗产妇低血压的血管升压药:过去、现在和未来。
Anaesthesia. 2015 Mar;70(3):252-7. doi: 10.1111/anae.13007. Epub 2015 Jan 13.
7
Epinephrine in anaphylaxis: higher risk of cardiovascular complications and overdose after administration of intravenous bolus epinephrine compared with intramuscular epinephrine.肾上腺素在过敏反应中的应用:与肌内注射肾上腺素相比,静脉推注肾上腺素后发生心血管并发症和用药过量的风险更高。
J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):76-80. doi: 10.1016/j.jaip.2014.06.007. Epub 2014 Aug 29.
8
A randomized controlled trial of variable rate phenylephrine infusion with rescue phenylephrine boluses versus rescue boluses alone on physician interventions during spinal anesthesia for elective cesarean delivery.一项在择期剖宫产脊髓麻醉期间,使用变率苯肾上腺素输注联合抢救性苯肾上腺素推注与单独使用抢救性苯肾上腺素推注比较,以评估对医生干预的随机对照试验。
Anesth Analg. 2014 Mar;118(3):611-8. doi: 10.1213/01.ane.0000437731.60260.ce.
9
A review of the impact of phenylephrine administration on maternal hemodynamics and maternal and neonatal outcomes in women undergoing cesarean delivery under spinal anesthesia.椎管内麻醉下剖宫产术中去氧肾上腺素对产妇血液动力学及母婴结局影响的研究综述。
Anesth Analg. 2012 Feb;114(2):377-90. doi: 10.1213/ANE.0b013e3182373a3e. Epub 2011 Nov 21.
10
Confusion about epinephrine dosing leading to iatrogenic overdose: a life-threatening problem with a potential solution.肾上腺素给药剂量混淆导致医源性用药过量:一个潜在的解决方案,可能危及生命的问题。
Ann Emerg Med. 2010 Apr;55(4):341-4. doi: 10.1016/j.annemergmed.2009.11.008. Epub 2010 Jan 19.

急诊科气管插管期间低血压时的推注式血管升压药:病例系列

Push-Dose Pressors During Peri-intubation Hypotension in the Emergency Department: A Case Series.

作者信息

Bakhsh Abdullah, Alotaibi Leena

机构信息

The King Abdulaziz University, Department of Emergency Medicine, Jeddah, Saudi Arabia.

The King Abdulaziz University, Faculty of Medicine, Jeddah, Saudi Arabia.

出版信息

Clin Pract Cases Emerg Med. 2021 Nov;5(4):390-393. doi: 10.5811/cpcem.2021.4.51161.

DOI:10.5811/cpcem.2021.4.51161
PMID:34813426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8610482/
Abstract

INTRODUCTION

Emergency physicians frequently encounter critically ill patients in circulatory shock requiring definitive airway procedures. Performing rapid sequence intubation in these patients without blood pressure correction has lethal complications. Questioning the efficacy and fearing side effects of push-dose pressors (PDP) has created an obstacle for their use in the emergency department (ED) setting. In this case series we describe the efficacy and side effects of PDP use during peri-intubation hypotension in the ED.

CASE SERIES

We included 11 patients receiving PDPs in this case series. The mean increase in systolic blood pressure was 41.3%, in diastolic blood pressure 44.3%, and in mean arterial pressure 35.1%. No adverse events were documented in this case series.

CONCLUSION

The use of push-dose pressors during peri-intubation hypotension may potentially improve hemodynamic status when used carefully in the ED.

摘要

引言

急诊医生经常会遇到处于循环性休克的重症患者,这些患者需要进行确定性气道操作。在未纠正血压的情况下对这些患者进行快速顺序插管会带来致命并发症。对推注剂量血管加压药(PDP)的疗效存疑以及担心其副作用,为其在急诊科的使用造成了障碍。在本病例系列中,我们描述了在急诊科围插管期低血压期间使用PDP的疗效和副作用。

病例系列

本病例系列纳入了11例接受PDP治疗的患者。收缩压平均升高41.3%,舒张压平均升高44.3%,平均动脉压平均升高35.1%。本病例系列中未记录到不良事件。

结论

在急诊科小心使用推注剂量血管加压药,可能会在围插管期低血压时改善血流动力学状态。