如何预防既往有妊娠期糖尿病的女性患2型糖尿病？行为干预的系统评价。
How to prevent type 2 diabetes in women with previous gestational diabetes? A systematic review of behavioural interventions.
作者信息
Pedersen Anne Louise Winkler, Terkildsen Maindal Helle, Juul Lise
机构信息
Department of Public Health, Section for Health Promotion and Health Services, Aarhus University, Bartholins Alle 2, DK 8000 Aarhus C, Denmark.
Department of Public Health, Section for Health Promotion and Health Services, Aarhus University, Bartholins Alle 2, DK 8000 Aarhus C, Denmark; Steno Diabetes Center Copenhagen, Health Promotion Research, Denmark.
出版信息
Prim Care Diabetes. 2017 Oct;11(5):403-413. doi: 10.1016/j.pcd.2017.05.002. Epub 2017 Jun 7.
OBJECTIVES
Women with previous gestational diabetes (GDM) have a seven times higher risk of developing type 2 diabetes (T2DM) than women without. We aimed to review the evidence of effective behavioural interventions seeking to prevent T2DM in this high-risk group.
METHODS
A systematic review of RCTs in several databases in March 2016.
RESULTS
No specific intervention or intervention components were found superior. The pooled effect on diabetes incidence (four trials) was estimated to: -5.02 per 100 (95% CI: -9.24; -0.80).
CONCLUSIONS
This study indicates that intervention is superior to no intervention in prevention of T2DM among women with previous GDM.
目的
既往患有妊娠期糖尿病（GDM）的女性患2型糖尿病（T2DM）的风险比未患GDM的女性高7倍。我们旨在综述寻求预防这一高危人群发生T2DM的有效行为干预措施的证据。
方法
2016年3月对多个数据库中的随机对照试验进行系统综述。
结果
未发现有特定干预措施或干预组成部分具有优越性。对糖尿病发病率的合并效应（四项试验）估计为：每100人中有-5.02例（95%置信区间：-9.24；-0.80）。
结论
本研究表明，在预防既往患有GDM的女性发生T2DM方面，干预优于不干预。
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