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老年人癫痫管理:来自医院癫痫发作管理国家审计(NASH)的经验教训。

Epilepsy management in older people: Lessons from National Audit of Seizure management in Hospitals (NASH).

作者信息

Ziso B, Dixon P A, Marson A G

机构信息

Dept. of Molecular and Clinical Pharmacology, University of Liverpool, Clinical Sciences Centre, Lower Lane, Fazakerley, L9 7LJ, United Kingdom.

出版信息

Seizure. 2017 Aug;50:33-37. doi: 10.1016/j.seizure.2017.05.002. Epub 2017 May 30.

DOI:10.1016/j.seizure.2017.05.002
PMID:28601689
Abstract

PURPOSE

Epilepsy is the third most common diagnosis in older people, however management in this group remains variable. National Audit of Seizure management in Hospitals (NASH) set out to assess care provided to patients attending hospitals in England following a seizure.

METHOD

154 Emergency Departments (EDs) across the UK took part. 1256 patients aged 60 years or over were included for analysis (median age 74 years, 54% men). 51% were known to have epilepsy, 17% had history of previous seizure or blackout and 32% presented with a suspected first seizure.

RESULTS

14% of older patients with epilepsy were not on treatment, 59% were on monotherapy. Sodium valproate was the most commonly used antiepileptic, 28%. 35% of patients with epilepsy, aged 60 and over, had a CT during admission compared to only 17% of those under 60. 80% of patients aged 60 and over presenting with a likely first seizure were admitted to hospital, compared to 65% of those under 60. 34% of those with suspected first seizure were referred to a neurologist on discharge compared to 68% of patients under the age of 60. 52% of 60-69year olds with a suspected first seizure were referred to neurology compared to 25% of patients aged 80-89.

CONCLUSIONS

Older patients presenting with seizures are more likely to be admitted to hospital and have imaging. They are less likely to be referred to specialist services on discharge. There appears to be significant disparity in patient age and rate of referral.

摘要

目的

癫痫是老年人中第三常见的诊断疾病,然而该群体的治疗方式仍存在差异。医院癫痫发作管理全国审计(NASH)旨在评估英格兰医院中癫痫发作患者所接受的护理。

方法

英国各地的154个急诊科参与了此项研究。纳入分析的患者为1256名60岁及以上的老年人(中位年龄74岁,男性占54%)。其中51%的患者已知患有癫痫,17%有既往癫痫发作或昏厥史,32%表现为疑似首次癫痫发作。

结果

14%的老年癫痫患者未接受治疗,59%接受单一疗法。丙戊酸钠是最常用的抗癫痫药物,占28%。60岁及以上的癫痫患者中,35%在住院期间进行了CT检查,而60岁以下患者这一比例仅为17%。60岁及以上首次癫痫发作可能性较大的患者中,80%入院治疗,而60岁以下患者这一比例为65%。疑似首次癫痫发作的患者中,34%在出院时被转诊至神经科医生处,而60岁以下患者这一比例为68%。60 - 69岁疑似首次癫痫发作的患者中,52%被转诊至神经科,而80 - 89岁患者这一比例为25%。

结论

癫痫发作的老年患者更有可能入院并接受影像学检查。他们出院时被转诊至专科服务的可能性较小。患者年龄和转诊率之间似乎存在显著差异。

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