Murray J B
J Gen Psychol. 1985 Jan;112(1):5-33. doi: 10.1080/00221309.1985.9710985.
The literature on lithium carbonate was reviewed for clues to the processes involved in mania. Lithium has proved effective therapeutically and prophylactically for mania and depressive disorders. Children and adolescents as well as adults tolerate lithium well. Side effects rarely are serious enough to necessitate having lithium therapy. Some success with schizophrenia and schizoaffective disorders has broadened the scope of lithium's therapeutic efficacy but also blunted the expectation for a direct relationship between lithium and the processes involved in mania. Research points to neurotransmitters as contributing to the etiology and symptom pattern of mania.
对碳酸锂相关文献进行了综述,以寻找与躁狂症发病过程有关的线索。锂已被证明在治疗和预防躁狂症及抑郁症方面有效。儿童、青少年和成年人对锂的耐受性良好。副作用很少严重到需要停止锂治疗。在精神分裂症和分裂情感性障碍方面取得的一些成功扩大了锂的治疗效果范围,但也降低了人们对锂与躁狂症发病过程之间直接关系的期望。研究表明神经递质与躁狂症的病因和症状模式有关。