Olaya-Garay Sandra X, Velásquez-Trujillo Paula A, Vigil-De Gracia Paulino
Hospital Universitario Hernando Moncaleano Perdomo, Neiva Huila, Colombia.
Universidad Libre, Cali, Colombia.
Int J Gynaecol Obstet. 2017 Sep;138(3):335-339. doi: 10.1002/ijgo.12237. Epub 2017 Jul 3.
To compare variables among adolescent and adult patients diagnosed with severe pre-eclampsia or eclampsia.
The present cross-sectional study enrolled patients with severe pre-eclampsia or eclampsia treated at an intensive care unit in Neiva, Colombia, between January 1 and November 30, 2014. Patients were stratified using age (younger than 20 years [adolescents] and aged at least 20 years [adults]) and patient variables were compared between groups. Maternal age, pregnancy duration at delivery, eclampsia, blood pressure, severe hypertension, maternal organ damage, HELLP syndrome, obstetric hemorrhage, laboratory findings, need for blood transfusion and fetal data were analyzed by group.
There were 171 patients enrolled; 154 (90.1%) with severe pre-eclampsia and 17 (9.9%) with eclampsia. There were 46 (26.9%) adolescent patients and 125 (73.1%) adults, and 13 (28.3%) and 4 (3.2%) patients had eclampsia in the adolescent and adult groups, respectively (P=0.001). The systolic (P=0.081), diastolic (P=0.174), and mean (P=0.102) blood pressure did not differ significantly between the groups but were higher in the adult group. The incidence of severe hypertension was significantly higher among adult patients (P=0.037).
The blood pressure used in defining pre-eclampsia and eclampsia should differ for adolescent patients in comparison with the rest of the population.
比较诊断为重度子痫前期或子痫的青少年患者与成年患者之间的各项变量。
本横断面研究纳入了2014年1月1日至11月30日期间在哥伦比亚内瓦市一家重症监护病房接受治疗的重度子痫前期或子痫患者。根据年龄(小于20岁[青少年]和至少20岁[成年人])对患者进行分层,并比较两组之间的患者变量。对产妇年龄、分娩时的孕周、子痫、血压、重度高血压、产妇器官损害、HELLP综合征、产科出血、实验室检查结果、输血需求和胎儿数据进行分组分析。
共纳入171例患者;154例(90.1%)为重度子痫前期,17例(9.9%)为子痫。青少年患者46例(26.9%),成年患者125例(73.1%),青少年组和成年组分别有13例(28.3%)和4例(3.2%)患者发生子痫(P=0.001)。两组之间的收缩压(P=0.081)、舒张压(P=0.174)和平均血压(P=0.102)差异无统计学意义,但成年组血压更高。成年患者中重度高血压的发生率显著更高(P=0.037)。
与其他人群相比,用于定义子痫前期和子痫的血压标准在青少年患者中应有所不同。