来自监测、流行病学和最终结果-医疗保险健康结果调查的老年癌症幸存者自我报告的跌倒、平衡或行走问题的患病率。

Prevalence of self-reported falls, balance or walking problems in older cancer survivors from Surveillance, Epidemiology and End Results-Medicare Health Outcomes Survey.

作者信息

Huang Min H, Blackwood Jennifer, Godoshian Monica, Pfalzer Lucinda

机构信息

Physical Therapy Department, School of Health Professions and Studies, University of Michigan - Flint, Flint, Michigan, United States.

出版信息

J Geriatr Oncol. 2017 Jul;8(4):255-261. doi: 10.1016/j.jgo.2017.05.008. Epub 2017 Jun 8.

DOI:10.1016/j.jgo.2017.05.008

PMID:28602712

Abstract

OBJECTIVE

To determine the prevalence of falls and balance/walking problems in the past 12months among older cancer survivors before and after cancer diagnosis.

MATERIALS AND METHODS

We analyzed cross-sectional data from individuals aged ≥65years with first primary cancer from the Surveillance, Epidemiology, and End Results and Medicare Health Outcomes Survey (SEER-MHOS) linkage (n=12,659). The first MHOS completed by each survivor from 0 to 2years before cancer diagnosis to 1-4years after cancer diagnosis were included. We estimated unadjusted and demographic-adjusted prevalence of falls and balance/walking problems for each type of cancer during five one-year time periods before and after cancer diagnosis.

RESULTS

Adjusted prevalence of falls was significantly higher post-diagnosis than pre-diagnosis in prostate (12% during years 1-2 pre-diagnosis vs. 17%-20% during years 1-4 post-diagnosis)(p=0.01) and lung cancer (17% during years 1-2 pre-diagnosis vs. 28% during years 1-2 post-diagnosis)(p=0.019). Adjusted prevalence of balance/walking problems were significantly higher post-diagnosis than pre-diagnosis in non-Hodgkin's lymphoma (26% during years 1-2 pre-diagnosis vs. 45% during years 1-2 post-diagnosis)(p=0.012), breast (32% during years 1-2 pre-diagnosis vs. 41% during years 3-4 post-diagnosis)(p=0.001), prostate (22% during years 1-2 pre-diagnosis vs. 28%-29% during years 1-4 post-diagnosis)(p=0.012), and lung cancer (33% during years 1-2 pre-diagnosis vs. 40% during year 0-1 pre-diagnosis and 46% during years 1-2 post-diagnosis)(p=0.018). Prevalence did not differ across time periods in other cancers.

CONCLUSIONS

Falls and balance/walking problems may become more frequent after the diagnosis of some cancers. Screening, surveillance, and interventions need to consider functional deficits and cancer diagnosis.

摘要

目的

确定老年癌症幸存者在癌症诊断前后过去12个月内跌倒及平衡/行走问题的发生率。

材料与方法

我们分析了来自监测、流行病学和最终结果以及医疗保险健康结果调查（SEER-MHOS）关联研究中年龄≥65岁的原发性癌症患者的横断面数据（n = 12,659）。纳入了每位幸存者在癌症诊断前0至2年至癌症诊断后1至4年期间完成的首次MHOS调查。我们估计了癌症诊断前后五个一年时间段内每种癌症跌倒及平衡/行走问题的未调整患病率和经人口统计学调整后的患病率。

结果

前列腺癌诊断后经调整的跌倒患病率显著高于诊断前（诊断前1 - 2年为12%，诊断后1 - 4年为17% - 20%）（p = 0.01），肺癌也是如此（诊断前1 - 2年为17%，诊断后1 - 2年为28%）（p = 0.019）。非霍奇金淋巴瘤诊断后经调整的平衡/行走问题患病率显著高于诊断前（诊断前1 - 2年为26%，诊断后1 - 2年为45%）（p = 0.012），乳腺癌（诊断前1 - 2年为32%，诊断后3 - 4年为41%）（p = 0.001），前列腺癌（诊断前1 - 2年为22%，诊断后1 - 4年为28% - 29%）（p = 0.012），以及肺癌（诊断前1 - 2年为33%，诊断前0 - 1年为40%，诊断后1 - 2年为46%）（p = 0.018）。其他癌症在各时间段的患病率无差异。