Anderson Chelsea, Olshan Andrew, Bae-Jump Victoria, Park Jihye, Brewster Wendy, Kent Erin, Nichols Hazel B
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Drive, Chapel Hill, NC, 27599, USA.
Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA.
Support Care Cancer. 2022 Jul;30(7):6339-6351. doi: 10.1007/s00520-022-07087-2. Epub 2022 Apr 28.
Functional status deficits are important quality of life concerns for older cancer survivors. We examined the prevalence of falls, walking/balance problems, and limitations in activities of daily living (ADLs) among older women with a history of endometrial cancer.
Cancer registry records from the Surveillance, Epidemiology, and End Results (SEER) program linked with Medicare Health Outcomes Survey (MHOS) data were used to identify endometrial cancer survivors aged ≥ 65 years who completed a survey ≥ 1 year after their cancer diagnosis (N = 3766), as well as an age- and race-matched group of women without a cancer history (N = 3766). We estimated prevalence ratios (PRs) to compare the prevalence of falls, walking or balance problems, and limitations in ADLs (bathing, dressing, eating, getting in/out of chairs, walking, using the toilet) between groups.
Difficulty with walking or balance was more common among survivors than the noncancer group (43% vs 36%; PR = 1.19; 95% CI: 1.10-1.27). Fall prevalence was similar between groups (endometrial cancer: 25%; noncancer: 26%; PR = 0.98; 95% CI: 0.89-1.08). Nearly half of endometrial cancer survivors (47%) reported at least one ADL limitation, with several activities (getting in/out of a chair, walking, bathing, using the toilet) more often limited among survivors than among women without cancer.
Functional impairments, especially problems with walking and/or balance, are common among older endometrial cancer survivors. Our results highlight the importance of addressing functional problems during the ongoing survivorship care of women with a history of endometrial cancer, with referral to rehabilitation or other relevant services when indicated.
功能状态缺陷是老年癌症幸存者生活质量的重要关注点。我们调查了有子宫内膜癌病史的老年女性中跌倒、行走/平衡问题以及日常生活活动（ADL）受限的发生率。
利用监测、流行病学和最终结果（SEER）项目的癌症登记记录与医疗保险健康结果调查（MHOS）数据相链接，以识别年龄≥65岁且在癌症诊断后≥1年完成调查的子宫内膜癌幸存者（N = 3766），以及一组年龄和种族匹配的无癌症病史女性（N = 3766）。我们估计患病率比（PR）以比较两组之间跌倒、行走或平衡问题以及ADL（洗澡、穿衣、进食、从椅子上起身/坐下、行走、使用厕所）受限的患病率。
幸存者中行走或平衡困难比非癌症组更常见（43%对36%；PR = 1.19；95%CI：1.10 - 1.27）。两组之间跌倒患病率相似（子宫内膜癌：25%；非癌症：26%；PR = 0.98；95%CI：0.89 - 1.08）。近一半的子宫内膜癌幸存者（47%）报告至少有一项ADL受限，在幸存者中，有几项活动（从椅子上起身/坐下、行走、洗澡、使用厕所）受限的情况比无癌症女性更常见。
功能障碍，尤其是行走和/或平衡问题，在老年子宫内膜癌幸存者中很常见。我们的结果强调了在有子宫内膜癌病史女性的持续生存护理期间解决功能问题的重要性，并在需要时转诊至康复或其他相关服务机构。
