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腹腔镜可调节胃束带术(LAGB)的长期疗效:一项瑞士单中心研究的结果,该研究对 405 例患者进行了长达 18 年的随访。

Long-term outcome of laparoscopic adjustable gastric banding (LAGB): results of a Swiss single-center study of 405 patients with up to 18 years' follow-up.

机构信息

Department of Surgery, St. Claraspital, Basel, Switzerland.

Department of Surgery, St. Claraspital, Basel, Switzerland.

出版信息

Surg Obes Relat Dis. 2017 Aug;13(8):1313-1319. doi: 10.1016/j.soard.2017.04.030. Epub 2017 Apr 29.

DOI:10.1016/j.soard.2017.04.030
PMID:28602794
Abstract

BACKGROUND

In the past, laparoscopic adjustable gastric banding (LAGB) seemed to be a promising bariatric procedure. However, many studies showed high rates of reoperation due to complications or insufficient weight loss. There is a lack of long-term studies with follow-up beyond 15 years.

OBJECTIVE

To conduct long-term follow-up of patients after LAGB and analyze their weight loss as a primary endpoint.

SETTING

Tertiary referral center for bariatric surgery, St. Claraspital, Switzerland.

METHODS

A retrospective analysis of prospectively collected clinical data in a cohort of 405 patients having undergone LAGB was performed.

RESULTS

A total of 405 patients (age 41±10 years, body mass index [BMI] 44.3±6 kg/m) were treated with LAGB between 1996 and 2010. Mean follow-up was 13±3 years, with a follow-up rate of 85% (range 8-18 years), corresponding to 343 patients. One hundred patients exceeded 15-year follow-up. In 216 patients (63%), sleeve gastrectomy, gastric bypass, or biliopancreatic diversion with duodenal switch was performed as revisional surgery. Twenty-seven patients (8%) refused revisional surgery after band removal. Finally, 100 patients (29%) still have the band in place, with a mean BMI of 35±7 kg/m, corresponding to an excess BMI loss of 48±27%. Among these, the failure rate was 25%, according to the Bariatric Analysis and Reporting Outcome System (BAROS); 50% had a good to excellent outcome.

CONCLUSION

More than 10 years after LAGB, 71% of patients lost their bands and only 15% of the 343 followed patients with the band in place have a good to excellent result, according to BAROS.

摘要

背景

过去,腹腔镜可调胃束带术(LAGB)似乎是一种有前途的减肥手术。然而,许多研究显示由于并发症或减重不足,需要进行高比例的再次手术。缺乏长期研究,随访时间超过 15 年。

目的

对 LAGB 后的患者进行长期随访,并分析其减重作为主要终点。

设置

瑞士圣克拉拉医院,三级转诊中心的减肥手术。

方法

对 405 例行 LAGB 治疗的患者前瞻性收集的临床数据进行回顾性分析。

结果

共有 405 名患者(年龄 41±10 岁,体重指数 [BMI] 44.3±6kg/m)于 1996 年至 2010 年接受 LAGB 治疗。平均随访时间为 13±3 年,随访率为 85%(范围为 8-18 年),对应 343 例患者。100 例患者随访时间超过 15 年。在 216 例(63%)患者中,行袖状胃切除术、胃旁路术或胆胰分流术加十二指肠转位术作为修正手术。27 例(8%)患者在去除束带后拒绝进行修正手术。最终,100 例(29%)患者仍保留束带,平均 BMI 为 35±7kg/m,对应的超重 BMI 减轻了 48±27%。在这些患者中,根据肥胖分析和报告结果系统(BAROS),失败率为 25%;50%的患者有良好到极好的结果。

结论

在 LAGB 后 10 年以上,根据 BAROS,71%的患者失去了束带,仅有 15%的 343 例随访患者保留束带且结果良好到极好。

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