Carandina Sergio, Tabbara Malek, Galiay Leila, Polliand Claude, Azoulay Daniel, Barrat Christophe, Lazzati Andrea
Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Digestive and Metabolic Surgery, Avicenne University Hospital, Centre Intégré Nord Francilien de la prise en charge de l'Obésité (CINFO), Université Paris XIII-UFR SMBH "Léonard de Vinci", Rue de Stalingrad, Bobigny, France.
Assistance Publique-Hôpitaux de Paris (AP-HP), Department of HPB Surgery and Liver Transplant Unit, Henri Mondor University Hospital-Creteil Hospital, Université Paris-Est Creteil Val de Marne, Avenue du Maréchal de Lattre de Tassigny-Avenue de Verdun,, 94000, Creteil, France.
Obes Surg. 2017 Apr;27(4):889-895. doi: 10.1007/s11695-016-2391-x.
Obesity is a chronic disease that requires procedures to enable to maintain good long-term results. Laparoscopic adjustable gastric banding (LAGB) studies with a long-term follow-up are limited and have often given conflicting results. We report our results in terms of banding life span and weight loss in a cohort of 301 patients operated on LAGB with a minimum follow-up of 10 years.
All patients who underwent LAGB at our university hospital between 1998 and 2004 were included in this study. The main outcome was band survival and complications that led to band removal, and the secondary outcome was weight loss. We present raw data and data after imputation for patients lost at follow-up.
Most patients were women (83 %), and the mean body mass index (BMI) baseline was 45.2 ± 6.7. The pars flaccida technique was performed in 50.9 % of the patients. All patients had at least 10 years of follow-up (range 10-16 years). Data were available at 10 years for 79.7 % and at 15 years for 80.6 %. Band survival was 65.8 % at 10 years and 53.3 % at 15 years. Mean excess weight loss (EWL) at 5, 10, and 15 years was 41.4, 38.7, and 35.1 %, respectively.
Despite the encouraging short-term results, LAGB shows long-term disappointing results in terms of weight loss and complication rates. The removal rate increases with time (about 3-4 % per year), and at 15 years, almost half of the bands had been removed.
肥胖是一种慢性疾病，需要采取措施以维持良好的长期效果。长期随访的腹腔镜可调节胃束带术（LAGB）研究有限，且结果常常相互矛盾。我们报告了301例行LAGB手术患者队列的束带使用寿命和体重减轻情况，这些患者的最短随访时间为10年。
本研究纳入了1998年至2004年间在我们大学医院接受LAGB手术的所有患者。主要结局是束带存活情况以及导致束带移除的并发症，次要结局是体重减轻。我们呈现了原始数据以及对失访患者进行插补后的数据。
大多数患者为女性（83%），平均体重指数（BMI）基线为45.2±6.7。50.9%的患者采用了松弛部技术。所有患者的随访时间至少为10年（范围为10至16年）。10年时有79.7%的数据可用，15年时有80.6%的数据可用。10年时束带存活率为65.8%，15年时为53.3%。5年、10年和15年时的平均超重减轻（EWL）分别为41.4%、38.7%和35.1%。
尽管短期结果令人鼓舞，但LAGB在体重减轻和并发症发生率方面的长期结果令人失望。移除率随时间增加（每年约3 - 4%），到15年时，几乎一半的束带已被移除。
