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一种循序渐进的方法:减少儿童肌张力障碍型脑瘫深部脑刺激中的感染

A Stepwise Approach: Decreasing Infection in Deep Brain Stimulation for Childhood Dystonic Cerebral Palsy.

作者信息

Johans Stephen J, Swong Kevin N, Hofler Ryan C, Anderson Douglas E

机构信息

1 Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL, USA.

出版信息

J Child Neurol. 2017 Sep;32(10):871-875. doi: 10.1177/0883073817713900. Epub 2017 Jun 12.

Abstract

Dystonia is a movement disorder characterized by involuntary muscle contractions, which cause twisting movements or abnormal postures. Deep brain stimulation has been used to improve the quality of life for secondary dystonia caused by cerebral palsy. Despite being a viable treatment option for childhood dystonic cerebral palsy, deep brain stimulation is associated with a high rate of infection in children. The authors present a small series of patients with dystonic cerebral palsy who underwent a stepwise approach for bilateral globus pallidus interna deep brain stimulation placement in order to decrease the rate of infection. Four children with dystonic cerebral palsy who underwent a total of 13 surgical procedures (electrode and battery placement) were identified via a retrospective review. There were zero postoperative infections. Using a multistaged surgical plan for pediatric patients with dystonic cerebral palsy undergoing deep brain stimulation may help to reduce the risk of infection.

摘要

肌张力障碍是一种运动障碍,其特征为不自主的肌肉收缩,可导致扭转运动或异常姿势。深部脑刺激已被用于改善由脑瘫引起的继发性肌张力障碍患者的生活质量。尽管深部脑刺激是治疗儿童肌张力障碍性脑瘫的一种可行选择,但它在儿童中与高感染率相关。作者介绍了一小系列肌张力障碍性脑瘫患者,他们采用逐步方法进行双侧内侧苍白球深部脑刺激植入,以降低感染率。通过回顾性研究确定了4例患有肌张力障碍性脑瘫且共接受了13次外科手术(电极和电池植入)的儿童。术后感染率为零。对于接受深部脑刺激的儿童肌张力障碍性脑瘫患者,采用多阶段手术计划可能有助于降低感染风险。

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