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颅外颈动脉疾病的综合治疗

Hybrid Treatment of Extracranial Carotid Artery Disease.

作者信息

Bozzay Joseph, Broce Mike, Mousa Albeir Y

机构信息

1 Department of Surgery, Walter Reed National Military Medical Center, Bethesda, MD, USA.

2 Center for Health Services and Outcomes Research, Charleston Area Medical Center Health Education and Research Institute, Charleston, WV, USA.

出版信息

Vasc Endovascular Surg. 2017 Aug;51(6):373-376. doi: 10.1177/1538574417710374. Epub 2017 Jun 11.

Abstract

OBJECTIVE

High-degree stenosis of both innominate (IA) or left common carotid artery (CCA) and carotid bifurcation is uncommon but still represents a significant challenge to interventionists in many aspects including techniques, timing, and priority. There are several strategies for intervention that have been reported in the literature. A well-described, less-invasive strategy for extracranial tandem carotid lesions is concomitant carotid endarterectomy (CEA) with retrograde carotid angioplasty and stenting (CAS). In this study, we examine intermediate-term outcomes of this hybrid procedure and review other described treatments.

METHODS

Electronic medical records of all patients who underwent hybrid (ostial CAS and CEA) procedures in a tertiary center over the last 10 years were reviewed. High-degree stenosis of the IA or CCA was defined according to North American Symptomatic Carotid Endarterectomy Trial criteria.

RESULTS

A total of 6 patients were identified. The population included 4 males and 2 females with a median age of 65 years. Five patients were symptomatic and all had stenosis >75% by angiography. Five of the patients underwent left CEA with proximal stenting and one patient underwent right-sided CEA with proximal stenting. Combined 30-day mortality and stroke rate was 0%. No restenosis, stroke, heart attack, or death occurred during a follow-up range of 1 to 36 months (mean 12.8 months, median 7.8 months).

CONCLUSION

The combined CEA with retrograde stenting for tandem extracranial lesion procedure is safe and feasible, with adequate intermediate-term outcomes consistent with the recent literature.

摘要

目的

无名动脉(IA)或左颈总动脉(CCA)以及颈动脉分叉处的高度狭窄并不常见,但在技术、时机和优先级等许多方面仍对介入医生构成重大挑战。文献中已报道了几种干预策略。一种描述详尽、侵入性较小的颅外串联颈动脉病变治疗策略是同期进行颈动脉内膜切除术(CEA)与逆行颈动脉血管成形术和支架置入术(CAS)。在本研究中,我们检查了这种混合手术的中期结果,并回顾了其他已描述的治疗方法。

方法

回顾了过去10年在一家三级中心接受混合手术(开口处CAS和CEA)的所有患者的电子病历。IA或CCA的高度狭窄根据北美症状性颈动脉内膜切除术试验标准定义。

结果

共确定了6例患者。该人群包括4名男性和2名女性,中位年龄为65岁。5例患者有症状,血管造影显示所有患者狭窄均>75%。5例患者接受了左侧CEA并近端置入支架,1例患者接受了右侧CEA并近端置入支架。30天联合死亡率和卒中率为0%。在1至36个月(平均12.8个月,中位7.8个月)的随访期内未发生再狭窄、卒中、心脏病发作或死亡。

结论

同期进行CEA与逆行支架置入术治疗串联颅外病变的手术是安全可行的,中期结果良好,与近期文献一致。

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