Hassan Moin, Mubarik Ateeq, Patel Chirag, Haq Furqan, Muddassir Salman
Internal Medicine, North Shore Medical Center, Salem, USA.
Internal Medicine, Oak Hill Hospital, Brooksville, USA.
Cureus. 2019 Jan 25;11(1):e3961. doi: 10.7759/cureus.3961.
Supra-aortic atherosclerotic lesions, including innominate artery atheromas, are an uncommon but established cause of transient ischemic attacks, stroke, upper extremity ischemia, and vertebrobasilar insufficiency. We present a patient with a transient ischemic attack admitted with right hemispheric symptoms who was found to have a severe ulcerated innominate artery atheroma. The patient underwent an aortic arch angiogram with stenting of the innominate artery. The proper diagnosis, treatment, and management of innominate artery atheromas are imperative to prevent further cardiovascular morbidity and mortality in patients. Currently, both endovascular and surgical options are available for revascularization, and there have been no randomized controlled trials comparing endovascular versus open repair to standardize one as the standard of care over the other. No randomized controlled trials are examining the benefit of dual versus single antiplatelet therapy post-stenting in supra-aortic atherosclerotic lesions. We believe that this topic warrants further research and needs evidence-based guidelines to help direct physicians about treatment and management.
主动脉弓上动脉粥样硬化病变,包括无名动脉粥样瘤,是短暂性脑缺血发作、中风、上肢缺血和椎基底动脉供血不足的少见但已明确的病因。我们报告一例因右侧半球症状入院的短暂性脑缺血发作患者,发现其患有严重的溃疡性无名动脉粥样瘤。该患者接受了主动脉弓血管造影及无名动脉支架置入术。正确诊断、治疗和管理无名动脉粥样瘤对于预防患者进一步发生心血管疾病的发病率和死亡率至关重要。目前,血管内治疗和外科手术都可用于血运重建,尚无随机对照试验比较血管内修复与开放修复,以将其中一种确立为优于另一种的标准治疗方法。也没有随机对照试验研究在主动脉弓上动脉粥样硬化病变支架置入术后双联抗血小板治疗与单联抗血小板治疗的益处。我们认为这个主题值得进一步研究,并且需要基于证据的指南来帮助指导医生进行治疗和管理。