纳米颗粒安全性评估：基于吸光度校正的毒性测试。
Assessment of nanoparticles' safety: corrected absorbance-based toxicity test.
机构信息
Powder Technology Laboratory, Institute of Materials, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
出版信息
Analyst. 2017 Jun 26;142(13):2338-2342. doi: 10.1039/c7an00382j.
PMID:28604847
Abstract
We developed a method to correct absorbance-based toxicity tests to remove the influence of the deposited dose of nanoparticles. As a model of absorbance-based toxicity tests, we chose the frequently used MTS test. The corrected cell viabilities obtained with the MTS test matched the results of the fluorescence-based PrestoBlue® test.
摘要
我们开发了一种方法来修正基于吸光度的毒性测试，以去除纳米颗粒沉积剂量的影响。作为基于吸光度的毒性测试的模型，我们选择了常用的 MTS 测试。用 MTS 测试修正后的细胞活力与基于荧光的 PrestoBlue®测试的结果相匹配。
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