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异基因造血干细胞移植候选者的牙周状况

Periodontal status of candidates for allogeneic hematopoietic stem cell transplantation.

作者信息

Nuernberg Marta Aparecida Alberton, Rodrigues Suelen Caroline, Perdoncini Nicole Nichele, Funke Vaneuza Araújo Moreira, Bonfim Carmem Maria Sales, Nabhan Samir Kanaan, Torres-Pereira Cassius Carvalho

机构信息

Avenida Prefeito Lothário Meissner, 632, Jardim Botânico, Curitiba, Paraná, Brazil, 80210-170.

出版信息

Spec Care Dentist. 2017 Jul;37(4):187-193. doi: 10.1111/scd.12229. Epub 2017 Jun 12.

DOI:10.1111/scd.12229
PMID:28605044
Abstract

PURPOSE

The aim of this study was to describe the periodontal profile of -candidates for allogeneic hematopoietic stem cell transplantation.

METHODS

This cross-sectional prospective study was performed from March 2014 to March 2015. After an initial interview, eligible individuals were evaluated by the following clinical parameters: visible plaque, bleeding on probing, probing depth, and clinical attachment level at six sites per tooth, excluding third molars.

RESULTS

Thirty-six candidates for allogeneic hematopoietic stem cell transplantation (HSCT) were clinically assessed. Eight (22%) patients were diagnosed with gingivitis and 21 (58%) of them with periodontitis. The gingival bleeding was statistically correlated with the percentage of sites with visible plaque (p < 0.0001; r = 0.630) and did not correlate with the number of platelets (p = 0.643, r = -0.082).

CONCLUSIONS

The candidates for allogeneic HSCT studied showed a high prevalence of periodontal diseases with unmonitored local infection before transplantation.

摘要

目的

本研究旨在描述异基因造血干细胞移植候选者的牙周状况。

方法

本横断面前瞻性研究于2014年3月至2015年3月进行。在初次访谈后,符合条件的个体通过以下临床参数进行评估:可见菌斑、探诊出血、探诊深度以及每颗牙齿六个部位(不包括第三磨牙)的临床附着水平。

结果

对36名异基因造血干细胞移植(HSCT)候选者进行了临床评估。8名(22%)患者被诊断为牙龈炎,其中21名(58%)患有牙周炎。牙龈出血与可见菌斑部位的百分比在统计学上相关(p < 0.0001;r = 0.630),与血小板数量无关(p = 0.643,r = -0.082)。

结论

所研究的异基因HSCT候选者显示牙周疾病患病率较高,移植前存在未受监测的局部感染。

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