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[全髋关节置换术后引流效果及安全性的Meta分析]

[Meta analysis of the efficacy and safety of drainage after total hip arthroplasty].

作者信息

Hou N, Jing F, Rong W, He D W, Zhu J J, Fang L, Sun C J

机构信息

Department of Orthopedic, Yucheng People's Hospital, Shandong 251200, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2017 Jun 6;97(21):1668-1672. doi: 10.3760/cma.j.issn.0376-2491.2017.21.016.

Abstract

To determine whether suction drainage is safe and effective compared with no-drainage in total hip arthroplasty. The research was based on PubMed, MEDLINE, EMBASE, Highwire, the Cochrane Library, CBM, CNKI, VIP and WFSD.The data were analysed using RevMan 5.2.Twenty-seven randomised controlled trials involving 3 603 hips were included in the analysis. The meta-analysis indicate that suction drainage increases the rate of homologous blood transfusion (=1.98, 95%: 1.49-2.64, <0.000 01)and the length of stay (=0.66, 95%: -0.01-1.33, =0.05) (<0.05). No significant difference was observed in the incidence of infection(=0.80, 95%: 0.52-1.22, =0.30), wound haematomas(=0.47, 95%: 0.21-1.10, =0.08), oozing (=0.93, 95%: 0.63-1.36, =0.71) , deep venous thrombosis(=2.12, 95%: 0.68-6.56, =0.19), VAS(=-0.06, 95%: -0.37-0.24, =0.68) when the drainage group was compared with the no-drainage group. The comparison between suction drainage and no drainage in THA have indicated that no-drainage for easy total hip arthroplasty may be a better choice. However, orthopedic surgeon need to weigh the pros and cons of no-drainage in some complicated THAs.

摘要

为了确定在全髋关节置换术中,与不引流相比,负压引流是否安全有效。该研究基于PubMed、MEDLINE、EMBASE、Highwire、Cochrane图书馆、中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普资讯(VIP)和万方数据知识服务平台(WFSD)。使用RevMan 5.2对数据进行分析。分析纳入了27项涉及3603个髋关节的随机对照试验。荟萃分析表明,负压引流会增加同种异体输血率(比值比=1.98,95%置信区间:1.49 - 2.64,P<0.00001)和住院时间(均值差=0.66,95%置信区间:-0.01 - 1.33,P = 0.05)(P<0.05)。在感染发生率(比值比=0.80,95%置信区间:0.52 - 1.22,P = 0.30)、伤口血肿发生率(比值比=0.47,95%置信区间:0.21 - 1.10,P = 0.08)、渗血发生率(比值比=0.93,95%置信区间:0.63 - 1.36,P = 0.71)、深静脉血栓发生率(比值比=2.12,95%置信区间:0.68 - 6.56,P = 0.19)、视觉模拟评分法(VAS)评分(均值差=-0.06,95%置信区间:-0.37 - 0.24,P = 0.68)方面,引流组与不引流组相比未观察到显著差异。全髋关节置换术中负压引流与不引流的比较表明,对于简单的全髋关节置换术,不引流可能是更好的选择。然而,骨科医生在一些复杂的全髋关节置换术中需要权衡不引流的利弊。

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