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[全膝关节置换术的闭式吸引引流或不引流:一项荟萃分析]

[Closed suction drainage or non-drainage for total knee arthroplasty: a meta-analysis].

作者信息

Zhang Xiao-nan, Wu Gang, Xu Rui-ze, Bai Xi-zhuang

机构信息

Department of Orthopaedics, the First Hospital of China Medical University, Shenyang, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2012 Dec;50(12):1119-25.

Abstract

OBJECTIVES

To investigate the different effects of closed suction drainage and non-drainage for total knee arthroplasty(TKA) and to provide reference information for the choice of clinical treatment.

METHODS

Randomized controlled trials (RCTs) of closed suction drainage versus non-drainage for TKA were collected from the Cochrane Library, PubMed, EMBase, Springer, CBM, CNKI, VIP and WANFANG database. Methodological quality of the RCTs was independently assessed using the Consolidated Standards of Reporting Trials (CONSORT) checklist. Data analysis was performed by RevMan Version 5.1.6 based on the methods recommended by the Cochrane Collaboration.

RESULTS

Twenty-one RCTs without bias were finally enrolled, and 1920 enrolled knees were identified into drainage group (979 knees) and non-drainage group (941 knees). A lower incidence of soft tissue ecchymosis was demonstrated in the closed suction drainage group (OR = 0.30, 95%CI: 0.24 - 0.49); however, compared with the non-drainage group, more loss of blood (MD = 320.03, 95%CI: 235.31 - 404.76) and more need of homologous blood transfusion (OR = 1.83, 95%CI: 1.26 - 3.29) were found in the closed suction drainage group. In addition, there were no significant differences of postoperative infection (OR = 0.53, 95%CI: 0.22 - 1.32), deep venous thrombosis (OR = 1.00, 95%CI: 0.46 - 2.18), and the joint range of motion (MD = -0.04, 95%CI: -1.11 - 1.02) between the two groups.

CONCLUSION

Based on the current evidence, no obvious advantage is demonstrated for closed suction drainage, in comparison with non-drainage for TKA.

摘要

目的

探讨全膝关节置换术(TKA)中闭式负压引流与不引流的不同效果,为临床治疗方案的选择提供参考依据。

方法

从Cochrane图书馆、PubMed、EMBase、Springer、中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普资讯(VIP)及万方数据库中收集关于TKA闭式负压引流与不引流的随机对照试验(RCT)。采用《报告试验的统一标准》(CONSORT)清单对纳入的RCT进行独立的方法学质量评估。依据Cochrane协作网推荐的方法,使用RevMan 5.1.6软件进行数据分析。

结果

最终纳入21项无偏倚的RCT,共1920例膝关节被分为引流组(979例)和不引流组(941例)。闭式负压引流组软组织瘀斑发生率较低(OR = 0.30,95%CI:0.24 - 0.49);然而,与不引流组相比,闭式负压引流组失血更多(MD = 320.03,95%CI:235.31 - 404.76),且更需要输同源血(OR = 1.83,95%CI:1.26 - 3.29)。此外,两组在术后感染(OR = 0.53,95%CI:0.22 - 1.32)、深静脉血栓形成(OR = 1.00,95%CI:0.46 - 2.18)及关节活动范围(MD = -(此处原文有误,推测应为0.04,95%CI:-1.11 - 1.02))方面无显著差异。

结论

基于当前证据,与TKA不引流相比,闭式负压引流未显示出明显优势。

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