Smith S B
Postgrad Med. 1985 Jun;77(8):42-5, 49-50. doi: 10.1080/00325481.1985.11699023.
Exercise-induced bronchospasm, a very common component of asthma, may be quite bothersome and interfere with activities. The etiology appears to be related to the degree of heat loss in the tracheobronchial tree and to release of mediators from the mast cells. Exercise-induced asthma can be effectively treated, preferably with preventive medications such as beta 2 agonists or cromolyn (Intal). In the future, drugs such as nifedipine (Procardia) may also be useful, but as yet no calcium channel blocker has been approved for this indication.
运动诱发性支气管痉挛是哮喘非常常见的一个症状,可能会相当令人困扰并妨碍日常活动。其病因似乎与气管支气管树的热量散失程度以及肥大细胞释放介质有关。运动诱发性哮喘可以得到有效治疗,最好使用预防性药物,如β2激动剂或色甘酸钠(因他舒)。未来,硝苯地平(心痛定)等药物可能也会有用,但目前尚无钙通道阻滞剂获批准用于这一适应症。