Dibilio Valeria, Nicoletti Alessandra, Mostile Giovanni, Portaro Giacomo, Luca Antonina, Patti Francesco, Zappia Mario
Dip. Scienze Mediche, Chirurgiche e Tecnologie Avanzate "G.F. Ingrassia", Università degli Studi di Catania, Catania, Italy.
Dip. Scienze Mediche, Chirurgiche e Tecnologie Avanzate "G.F. Ingrassia", Università degli Studi di Catania, Catania, Italy.
Neurosci Lett. 2017 Jul 27;654:38-41. doi: 10.1016/j.neulet.2017.06.006. Epub 2017 Jun 9.
In Parkinson's Disease (PD), effects of a cognitive training have been systematically evaluated only for cognitive and behavioral outcome measures, with mild to moderate effects. Despite the demonstrated interplay between cognition and gait, no studies have investigated the effect of cognitive rehabilitation protocols on gait in PD.
Patients affected by PD with freezing of gait were treated twice a week for six weeks with one hour sessions of computer-assisted training of attention ability and information processing tasks. Gait parameters were recorded at baseline, after six weeks and at three months.
Seven patients completed the evaluations at six weeks, six patients at three months. We observed at six weeks a significant reduction in both legs cycle duration, with an increment in mean velocity and cadence. Bilateral cycle and step lengths increased even if not significantly. No significant differences in gait parameters were detected at three months with respect to the baseline.
This pilot study suggests that a computer-assisted rehabilitation protocol based on executive functions training could improve walking in PD patients with freezing of gait.
在帕金森病（PD）中，认知训练的效果仅针对认知和行为结果指标进行了系统评估，效果为轻度至中度。尽管已证明认知与步态之间存在相互作用，但尚无研究调查认知康复方案对PD患者步态的影响。
对患有步态冻结的PD患者每周进行两次治疗，为期六周，每次一小时，进行注意力能力和信息处理任务的计算机辅助训练。在基线、六周后和三个月时记录步态参数。
七名患者在六周时完成评估，六名患者在三个月时完成评估。我们在六周时观察到双腿周期持续时间显著缩短，平均速度和步频增加。双侧周期和步长增加，尽管不显著。三个月时与基线相比，步态参数未检测到显著差异。
这项初步研究表明，基于执行功能训练的计算机辅助康复方案可以改善患有步态冻结的PD患者的行走能力。
