Mehta Krunal D, Gelotar Prakash S, Vachhani Swati C, Makwana Naresh, Sinha Mala
Department of Microbiology, Shri MP Shah Government Medical College, Jamnagar, India.
Department of PSM, Shri MP Shah Government Medical College, Jamnagar, India.
WHO South East Asia J Public Health. 2014 Jan-Mar;3(1):72-74. doi: 10.4103/2224-3151.206888.
Background and Methods India is one of the countries in the World Health Organization South-East Asia Region that regularly reports outbreaks of dengue fever (DF)/dengue hemorrhagic fever (DHF). As effective control and preventive programmes depend upon improved surveillance data, this study was carried out to report the seroprevalence of dengue virus infection in an area around Jamnagar city, Western India. [1] Methods The laboratory records of clinically suspected dengue patients from July 2008 to June 2011 were analysed retrospectively for the results of immunoglobulin M (IgM) anti-dengue antibodies, tested by dengue monoclonal antibody (IgM) capture enzyme-linked immunosorbent assay (MAC ELISA). Variations in disease incidence by sex, age group and season were assessed. Results A total of 903 serum samples were tested, of which 253 were positive. The majority were males (72%) and in the age group of 16-30 years. The incidence of dengue peaked in October and slowly tapered by December. Conclusion Dengue cases were higher during September to December, in the post-monsoon season. This observation is useful for planning special preventive strategies. The study draws attention to the susceptibility of the male, young adult age group.
背景与方法 印度是世界卫生组织东南亚区域定期报告登革热（DF）/登革出血热（DHF）疫情的国家之一。由于有效的控制和预防计划依赖于改进的监测数据，本研究旨在报告印度西部贾姆讷格尔市周边地区登革热病毒感染的血清流行率。[1] 方法 回顾性分析2008年7月至2011年6月临床疑似登革热患者的实验室记录，以获取通过登革热单克隆抗体（IgM）捕获酶联免疫吸附测定（MAC ELISA）检测的免疫球蛋白M（IgM）抗登革热抗体结果。评估疾病发病率在性别、年龄组和季节方面的差异。结果 共检测了903份血清样本，其中253份呈阳性。大多数为男性（72%），年龄在16 - 30岁组。登革热发病率在10月达到峰值，到12月逐渐下降。结论 在季风后季节，9月至12月期间登革热病例较多。这一观察结果有助于制定特殊的预防策略。该研究提醒人们关注男性青年成年人群体的易感性。
