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与瑞典同一地理区域的历史上未经治疗的多发性硬化症人群相比,当代多发性硬化症人群的工作能力有所提高。

Improved working ability in a contemporary MS population compared with a historic non-treated MS population in the same geographic area of Sweden.

作者信息

Wickström Anne, Sundström Peter, Wickström Lucas, Dahle Charlotte, Vrethem Magnus, Svenningsson Anders

机构信息

Department of Pharmacology and Clinical Neuroscience, Umeå University, Sweden.

Department of Software Engineering, Blekinge Institute of Technology, Sweden.

出版信息

Mult Scler J Exp Transl Clin. 2015 Sep 22;1:2055217315608203. doi: 10.1177/2055217315608203. eCollection 2015 Jan-Dec.

Abstract

BACKGROUND

Multiple sclerosis (MS) often causes a reduced ability to work. Improved disease control as well as adjustment of working conditions may improve work ability in MS.

OBJECTIVES

The objective of this article is to compare the degree of sickness absence in two MS populations that either have or have not received disease-modifying drug (DMD) treatments or active work-promoting measures.

METHODS

We investigated the occurrence of sickness absence in MS patients living in Västerbotten County, Sweden, in 2013, in which the majority of MS patients receive DMD treatment. The result was compared with a previous survey in the same area during a period when no DMD was available and no work-promoting measures for MS patients were practiced.

RESULTS

The proportion of MS patients active in the labor market or studying increased from 38% to 70% in the contemporary compared with the historic population ( < 0.001). The proportion of MS patients with a full-time disability pension decreased from 27% to 12% ( < 0.001). There was a significant decrease of sickness absence in several individual EDSS grades.

CONCLUSIONS

Our data indicate that treatment with DMDs combined with active work-promoting measures lead to improved work ability in MS.

摘要

背景

多发性硬化症(MS)常导致工作能力下降。改善疾病控制以及调整工作条件可能会提高MS患者的工作能力。

目的

本文的目的是比较两组MS患者的病假程度,一组接受了疾病修正药物(DMD)治疗或积极的促进工作措施,另一组则未接受。

方法

我们调查了2013年居住在瑞典韦斯特博滕郡的MS患者的病假情况,该郡大多数MS患者接受DMD治疗。将结果与该地区之前在没有DMD且未实施针对MS患者的促进工作措施期间的一项调查进行比较。

结果

与历史人群相比,当代活跃于劳动力市场或正在学习的MS患者比例从38%增至70%(<0.001)。领取全职残疾抚恤金的MS患者比例从27%降至12%(<0.001)。在几个不同的扩展残疾状态量表(EDSS)等级中,病假显著减少。

结论

我们的数据表明,DMD治疗与积极的促进工作措施相结合可提高MS患者的工作能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3e9/5433506/4873702de8b4/10.1177_2055217315608203-fig1.jpg

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