Seecheran Rajeev, Seecheran Valmiki, Persad Sangeeta, Lalla Sasha, Seecheran Naveen Anand
The University of the West Indies, Mt. Hope, Trinidad and Tobago.
North West Regional Health Authority, Port-of-Spain, Trinidad and Tobago.
J Investig Med High Impact Case Rep. 2017 Jun 1;5(2):2324709617712735. doi: 10.1177/2324709617712735. eCollection 2017 Apr-Jun.
Anaphylaxis is a sudden-onset, severe hypersensitivity reaction that can be potentially fatal. It can often transition to refractory hemodynamic instability, eventually resulting in death. Stress-related cardiomyopathies (SRCs) have multifactorial etiologies, including being linked to excessive catecholamine release in periods of intense stress. This novel case report recounts a SRC caused by contrast-induced anaphylaxis within 1 hour post percutaneous coronary intervention. Both acutely life-threatening conditions may occur simultaneously and are implicated with devastating complications. Further research is required to understand this cardiac-neuroaxis interplay in SRC to identify risk factors and develop management strategies.
过敏反应是一种突发的、严重的超敏反应，可能会危及生命。它常常会转变为难治性血流动力学不稳定，最终导致死亡。应激相关心肌病（SRC）病因多方面，包括与强烈应激期间儿茶酚胺过度释放有关。本病例报告讲述了1例经皮冠状动脉介入术后1小时内由造影剂诱发过敏反应导致的应激相关心肌病。这两种急性危及生命的情况可能同时发生，并伴有严重并发症。需要进一步研究以了解应激相关心肌病中心脏-神经轴的相互作用，从而识别危险因素并制定管理策略。
