Rosen L, Roseboom L E, Gubler D J, Lien J C, Chaniotis B N
Am J Trop Med Hyg. 1985 May;34(3):603-15. doi: 10.4269/ajtmh.1985.34.603.
Thirty-four strains of Asian and Pacific mosquitoes belonging to 22 species of 7 genera were compared for oral and/or parenteral susceptibility to infection with 1 or more strains of each of the 4 dengue serotypes. Surprisingly, several species of common man-biting Aedes were much more susceptible to oral infection with each of the 4 dengue serotypes than was Aedes aegypti. These species included Aedes albopictus and members of the scutellaris group of the subgenus Stegomyia found on South Pacific islands. Mosquito strains and species relatively susceptible to 1 dengue serotype usually were relatively susceptible to the others also. Almost all species of Aedes tested were uniformly susceptible to parenteral infection with the dengue viruses but, with the exception of a species of Tripteroides, species of all other genera were comparatively resistant to that mode of infection. Dengue viruses usually replicated to about the same extent in orally-infected mosquitoes as they did in parenterally-infected specimens of the same species. Seventeen species of mosquitoes of 7 genera also were tested for parenteral susceptibility to infection with Japanese encephalitis virus. With the possible exception of 2 species of Anopheles, the virus replicated to about the same degree in all species tested and achieved levels considerably higher than did any of the dengue viruses in the same mosquito strain and species held under the same conditions.
对属于7个属22个物种的34株亚太地区蚊子进行了比较，观察其对4种登革热血清型中每种血清型的1株或多株病毒的经口和/或经注射感染的易感性。令人惊讶的是，几种常见的叮人伊蚊对4种登革热血清型中每种血清型的经口感染比埃及伊蚊更易感。这些物种包括白纹伊蚊以及在南太平洋岛屿发现的覆蚊亚属斯氏类的成员。对1种登革热血清型相对易感的蚊株和物种通常对其他血清型也相对易感。几乎所有测试的伊蚊物种对登革热病毒的经注射感染均普遍易感，但除杵蚊属的1个物种外，所有其他属的物种对该感染方式相对有抗性。登革热病毒在经口感染的蚊子中的复制程度通常与在同一物种经注射感染的样本中的复制程度大致相同。还对7个属的17种蚊子进行了经注射感染日本脑炎病毒的易感性测试。除2种按蚊可能例外，该病毒在所有测试物种中的复制程度大致相同，且在相同条件下饲养的同一蚊株和物种中达到的水平明显高于任何登革热病毒。
