澳大利亚脑膜炎奈瑟菌血清群W克隆复合体11新的耐青霉素分支的克隆扩增
Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia.
作者信息
Mowlaboccus Shakeel, Jolley Keith A, Bray James E, Pang Stanley, Lee Yung Thin, Bew Jane D, Speers David J, Keil Anthony D, Coombs Geoffrey W, Kahler Charlene M
出版信息
Emerg Infect Dis. 2017 Aug;23(8):1364-1367. doi: 10.3201/eid2308.170259. Epub 2017 Aug 15.
Abstract
In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.
摘要
在西澳大利亚州，2016年，血清群W克隆复合体11的脑膜炎奈瑟菌成为侵袭性脑膜炎球菌病的主要病因。我们通过核心基因组分析表明出现了一个具有penA_253等位基因的耐青霉素分支。这个新的耐青霉素分支可能会影响该疾病的治疗方案。
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