López Mariana Beatriz, Lichtenberger Aldana, Conde Karina, Cremonte Mariana
Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental (Interdisciplinary Center of Mathematics and Experimental Psychology Research), Consejo Nacional de Investigaciones Científicas y Técnicas (National Council of Scientific and Technological Research, CONICET), Buenos Aires, Argentina.
Instituto de Psicología Básica, Aplicada y Tecnología (Institute of Basic Applied Psychology and Technology); Universidad Nacional de Mar del Plata; CONICET, Buenos Aires, Argentina.
Rev Bras Ginecol Obstet. 2017 Jul;39(7):322-329. doi: 10.1055/s-0037-1603744. Epub 2017 Jun 13.
Considering the physical, mental and behavioral problems related to fetal alcohol exposure, prenatal clinical guides suggest a brief evaluation of alcohol consumption during pregnancy to detect alcohol intake and to adjust interventions, if required. Even if any alcohol use should be considered risky during pregnancy, identifying women with alcohol use disorders is important because they could need a more specific intervention than simple advice to abstain. Most screening tests have been developed and validated in male populations and focused on the long-term consequences of heavy alcohol use, so they might be inappropriate to assess consumption in pregnant women. To analyze the internal reliability and validity of the alcohol screening instruments Alcohol Use Disorders Identification Test (AUDIT), Alcohol Use Disorders Identification Test - Consumption (AUDIT-C), Tolerance, Worried, Eye-Opener, Amnesia and Cut-Down (TWEAK), Rapid Alcohol Problems Screen - Quantity Frequency (RAPS-QF) and Tolerance, Annoyed, Cut-Down and Eye-Opener (T-ACE) to identify alcohol use disorders in pregnant women. A total of 641 puerperal women were personally interviewed during the 48 hours after delivery. The receiver operating characteristics (ROC) curves and the sensitivity and specificity of each instrument using different cut-off points were analyzed. All instruments showed areas under the ROC curves above 0.80. Larger areas were found for the TWEAK and the AUDIT. The TWEAK, the T-ACE and the AUDIT-C showed higher sensitivity, while the AUDIT and the RAPS-QF showed higher specificity. Reliability (internal consistency) was low for all instruments, improving when optimal cut-off points were used, especially for the AUDIT, the AUDIT-C and the RAPS-QF. In other cultural contexts, studies have concluded that T-ACE and TWEAK are the best instruments to assess pregnant women. In contrast, our results evidenced the low reliability of those instruments and a better performance of the AUDIT in this population.
考虑到与胎儿酒精暴露相关的身体、心理和行为问题,产前临床指南建议对孕期饮酒情况进行简要评估,以检测酒精摄入量,并在必要时调整干预措施。即使孕期任何饮酒行为都应被视为有风险,但识别有酒精使用障碍的女性很重要,因为她们可能需要比单纯建议戒酒更具体的干预措施。大多数筛查测试是在男性人群中开发和验证的,且侧重于大量饮酒的长期后果,因此可能不适用于评估孕妇的饮酒情况。为分析酒精筛查工具酒精使用障碍识别测试(AUDIT)、酒精使用障碍识别测试-消费量(AUDIT-C)、耐受性、担忧、清晨唤醒、失忆和减量(TWEAK)、快速酒精问题筛查-饮酒量频率(RAPS-QF)以及耐受性、烦恼、减量和清晨唤醒(T-ACE)在识别孕妇酒精使用障碍方面的内部信度和效度。共有641名产妇在分娩后48小时内接受了个人访谈。分析了各工具使用不同临界值时的受试者工作特征(ROC)曲线以及敏感性和特异性。所有工具的ROC曲线下面积均高于0.80。TWEAK和AUDIT的曲线下面积更大。TWEAK、T-ACE和AUDIT-C显示出较高的敏感性,而AUDIT和RAPS-QF显示出较高的特异性。所有工具的信度(内部一致性)较低,使用最佳临界值时有所改善,尤其是AUDIT、AUDIT-C和RAPS-QF。在其他文化背景下,研究得出结论,T-ACE和TWEAK是评估孕妇的最佳工具。相比之下,我们的结果证明了这些工具在该人群中的信度较低,而AUDIT的表现更好。