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双侧永存原始玻璃体增生症:视网膜母细胞瘤的模仿者。

Bilateral persistent fetal vasculature: mimicker of retinoblastoma.

作者信息

Kumar Jogender, Yadav Arushi

机构信息

Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Radiodiagnosis and Imaging, SMS Medical College and Hospital, Jaipur, Rajasthan, India.

出版信息

BMJ Case Rep. 2017 Jun 13;2017:bcr-2017-220879. doi: 10.1136/bcr-2017-220879.

Abstract

We describe a case of bilateral persistent fetal vasculature (PFV) in a 3-month-old boy who presented with bilateral white pupillary reflex and a possible diagnosis of retinoblastoma. On ultrasonography, there was an echogenic band in the posterior segment of both eyes which connected the posterior surface of the lens capsule to the optic disc. Colour Doppler revealed the presence of vascularity in the band along its entire length. No calcification or mass lesion was seen. These findings are diagnostic of PFV. Most cases of PFV are unilateral and sporadic in nature and closely mimic retinoblastoma. Although rare, PFV should be considered in the differential diagnosis when examining a case of bilateral leukocoria. Paediatricians should be aware of this rare but serious entity.

摘要

我们描述了一名3个月大男童双侧永存原始玻璃体增生症(PFV)的病例,该患儿表现为双侧白瞳症,初步诊断为视网膜母细胞瘤。超声检查显示双眼后段有一条强回声带,连接晶状体囊后表面与视盘。彩色多普勒显示该带全长均有血管。未见钙化或肿块病变。这些发现可诊断为PFV。大多数PFV病例为单侧且散发,与视网膜母细胞瘤极为相似。尽管罕见,但在检查双侧白瞳症病例时,鉴别诊断中应考虑PFV。儿科医生应了解这种罕见但严重的病症。

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