Srisuwanwattana Ploychompoo, Vachiramon Vasanop
Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Case Rep Dermatol. 2017 Mar 17;9(1):69-73. doi: 10.1159/000458406. eCollection 2017 Jan-Apr.
Necrolytic acral erythema (NAE) is a distinctive skin disorder. The exact cause and pathogenesis is still unclear. Most studies report an association of NAE with hepatitis C virus (HCV) infection. We report a 64-year-old woman who presented with chronic mildly pruritic brownish to erythematous rashes on both lateral malleoli for 7 months. The clinical and histopathological findings were compatible with NAE. However, the serologic marker for HCV was negative.
坏死性肢端红斑（NAE）是一种独特的皮肤疾病。确切病因和发病机制仍不清楚。大多数研究报告NAE与丙型肝炎病毒（HCV）感染有关。我们报告一名64岁女性，双侧外踝出现慢性轻度瘙痒性褐色至红斑皮疹7个月。临床和组织病理学表现符合NAE。然而，HCV血清学标志物为阴性。
