Yonkov D I
Methods Find Exp Clin Pharmacol. 1985 Mar;7(3):113-8.
Wistar rats were tested in open field immediately after training on a discriminative-motor task in a maze or after retention tests given 24 hr later. The animals were treated with CNS stimulants: caffeine, strychnine and amphetamine applied alone or in combination with atropine before or immediately after the training session. The CNS stimulants improved learning and retention of rats, increased their emotionality after acquisition and facilitated their habituation in the new environment in the period of retention. Atropine abolished both the memory and behavioral effects of the CNS stimulants. The results favor the view about common mechanisms in the memory effects of CNS stimulants.
在迷宫中进行辨别性运动任务训练后，或在24小时后进行记忆测试后，立即对Wistar大鼠进行旷场试验。在训练前或训练后立即给动物使用中枢神经系统兴奋剂：单独使用咖啡因、士的宁和苯丙胺，或与阿托品联合使用。中枢神经系统兴奋剂改善了大鼠的学习和记忆能力，在习得后增加了它们的情绪反应，并在记忆期促进了它们在新环境中的习惯化。阿托品消除了中枢神经系统兴奋剂的记忆和行为效应。这些结果支持了关于中枢神经系统兴奋剂记忆效应存在共同机制的观点。
