Schaefer Timothy J., Nunez Lopez Omar
University of Texas Medical Branch
Most small burns are treated at home or by local providers as outpatients. This topic focuses on the initial resuscitation and management of severe burns. (Also see Burns, Evaluation and Management and Burns, Thermal). The patient's age determines burn severity classification, the percentage of total body surface area burned (%TBSA), depth of burn, type of burn, and whether specific body parts are involved. Patients are classified as having severe burns if they have any of the following; >10% TBSA in children (<10 years old) or elderly (>50 years old). >20% TBSA in adults. > 5% full thickness; high-voltage electrical burns; significant burns to the face, eyes, ears, joints, or genitalia . Other factors that should be considered and increase the patient’s morbidity and mortality include associated inhalation injury, associated traumatic injury, and the patient’s baseline medical conditions like heart disease or lung disease. Several factors may predispose the specific group of patients to more complicated injuries. Severe burns cause not only significant injury at the local burn site but also a systemic response throughout the body. Inflammatory and vasoactive mediators such as histamines, prostaglandins, and cytokines are released, causing a systemic capillary leak, intravascular fluid loss, and large fluid shifts. These responses occur mostly over the first 24 hours, peaking around 6 to 8 hours after injury. This response, along with decreased cardiac output and increased vascular resistance, can lead to marked hypovolemia and hypoperfusion, called “burn shock.” This can be managed with aggressive fluid resuscitation and close monitoring for adequate, but not excessive, IV fluids.It is important to remember that burns alone do not cause significant hypotension initially, and “burn shock” develops over the first few hours. If the patient is profoundly hypotensive initially, other causes of hypotension should be sought.
大多数轻度烧伤患者在家庭或由当地医疗机构作为门诊病人进行治疗。本主题重点关注重度烧伤的初始复苏和处理。(另见《烧伤,评估与处理》以及《烧伤,热力烧伤》)。患者的年龄决定烧伤严重程度分级、烧伤占总体表面积的百分比(%TBSA)、烧伤深度、烧伤类型以及是否涉及特定身体部位。如果患者符合以下任何一种情况,则被归类为重度烧伤:儿童(<10岁)或老年人(>50岁)烧伤面积>10%TBSA;成年人烧伤面积>20%TBSA;全层烧伤面积>5%;高压电烧伤;面部、眼睛、耳朵、关节或生殖器的严重烧伤。其他应考虑的因素以及会增加患者发病率和死亡率的因素包括合并吸入性损伤、合并创伤性损伤以及患者的基础疾病,如心脏病或肺病。有几个因素可能使特定患者群体更容易发生更复杂的损伤。重度烧伤不仅会在局部烧伤部位造成严重损伤,还会引发全身反应。组胺、前列腺素和细胞因子等炎症和血管活性介质会释放出来,导致全身毛细血管渗漏、血管内液体丢失和大量液体转移。这些反应大多在最初24小时内发生,在受伤后约6至8小时达到峰值。这种反应,连同心输出量减少和血管阻力增加,可导致明显的血容量不足和灌注不足,即所谓的“烧伤休克”。这可以通过积极的液体复苏和密切监测以确保静脉输液量充足但不过量来处理。重要的是要记住,单纯烧伤最初不会导致明显的低血压,“烧伤休克”是在最初几个小时内发展起来的。如果患者最初就出现严重低血压,应寻找其他低血压原因。