Raj Marc A., Ranka Sagar, Goyal Amandeep
Bodor Clinic
University of Kansas
Hypertrophic obstructive cardiomyopathy (HOCM) is a relatively common disorder. Historically, it has been referred to as idiopathic hypertrophic subaortic stenosis. HOCM is a significant cause of sudden cardiac death in young people, including well-trained athletes, affecting men and women equally across all races. In most patients, it results from asymmetric septal hypertrophy, causing outflow obstruction of the left ventricle. Diagnosing and challenging medical health professionals in evaluating at-risk athletes is difficult. Unfortunately, HOCM is often not diagnosed until a significant cardiac event has occurred. The hypertrophy can occur in any segment of the left ventricle but is most common in the interventricular septum. This often results in obstruction of blood flow through the left ventricular outflow tract. HOCM is a genetic disorder. Defects in several genes have been identified that result in septal hypertrophy. The condition is usually asymptomatic in children but may first present with sudden death in teenagers and adolescents.
肥厚型梗阻性心肌病（HOCM）是一种相对常见的疾病。在历史上，它曾被称为特发性肥厚性主动脉瓣下狭窄。HOCM是年轻人包括训练有素的运动员心脏性猝死的重要原因，在所有种族中对男性和女性的影响相同。在大多数患者中，它是由不对称性室间隔肥厚导致左心室流出道梗阻引起的。诊断并考验医疗健康专业人员对有风险运动员进行评估是困难的。不幸的是，HOCM往往直到发生重大心脏事件才被诊断出来。肥厚可发生在左心室的任何节段，但最常见于室间隔。这通常会导致通过左心室流出道的血流受阻。HOCM是一种遗传性疾病。已经确定了几个导致室间隔肥厚的基因缺陷。这种情况在儿童中通常无症状，但可能在青少年中首先表现为猝死。
