Rokkanen P, Böstman O, Vainionpää S, Vihtonen K, Törmälä P, Laiho J, Kilpikari J, Tamminmäki M
Lancet. 1985 Jun 22;1(8443):1422-4. doi: 10.1016/s0140-6736(85)91847-1.
Biodegradable polylactide-glycolide copolymer implants for fracture fixation were developed and tested in rabbits. In a prospective clinical study 44 patients with a displaced fracture of the ankle were randomly allocated to two groups; one was treated with conventional metallic implants and the other with the biodegradable implants. There were no differences between the two groups in the early results, but the biodegradable fixation method is advantageous because the removal procedure associated with metallic implants is avoided.
用于骨折固定的可生物降解聚丙交酯-乙交酯共聚物植入物已研发成功并在兔子身上进行了测试。在一项前瞻性临床研究中,44例踝关节移位骨折患者被随机分为两组;一组采用传统金属植入物治疗,另一组采用可生物降解植入物治疗。两组早期结果无差异,但可生物降解固定方法具有优势,因为避免了与金属植入物相关的取出过程。