Donnenberg Vera S, Mandic Maja, Rhee John C, Burns Timothy F, Meibohm Bernd, Korth-Bradley Joan M
Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
J Clin Pharmacol. 2017 Aug;57(8):947-955. doi: 10.1002/jcph.938. Epub 2017 Jun 14.
Biologicals are a rapidly expanding class of medications used in the treatment of many different conditions. This article reviews the common characteristics of this class and the requirements for safe and effective use in patients. Several vignettes are included to illustrate common challenges.
生物制品是一类迅速发展的药物,用于治疗多种不同病症。本文综述了这类药物的共同特性以及在患者中安全有效使用的要求。文中包含了几个案例以说明常见的挑战。