Dickson D, Shave R, Rishniw M, Patteson M
HeartVets, Porthcawl, CF36 5LD, UK.
Cardiff School of Sport, Cardiff Metropolitan University, Cardiff, CF23 6XD, UK.
J Vet Cardiol. 2017 Aug;19(4):339-350. doi: 10.1016/j.jvc.2017.04.003. Epub 2017 Jun 12.
To establish reference intervals for echocardiographic measures of longitudinal left ventricular function in adult English Springer spaniel (ESS) dogs.
This study involved 42 healthy adult ESS.
Animals were prospectively recruited from a general practice population in the United Kingdom. Dogs were examined twice, at least 12 months apart, to exclude dogs with progressive cardiac disease. Mitral annular plane systolic excursion, tissue Doppler imaging mitral annular velocities and two-dimensional speckle-tracking echocardiographic left ventricular longitudinal strain and strain rate were measured. Intraoperator and intraobserver variability were examined and reference intervals were calculated. The potential effects of body weight, age and heart rate on these variables were examined.
Intraoperator and intraobserver variability was <10% for all parameters except tissue Doppler imaging E' (the peak velocity of early diastolic mitral annular motion as determined by pulsed wave Doppler) and two-dimensional speckle-tracking echocardiographic variables, which were all <20%. Thirty-nine dogs were used to create reference intervals. Significant (but mostly weak) effects of age, heart rate and body weight on were detected. Reference intervals were similar to previously published values in different breeds.
Breed specific reference intervals for measures of longitudinal left ventricular function in the ESS are presented.
建立成年英国激飞猎犬（ESS）左心室纵向功能超声心动图测量的参考区间。
本研究纳入了42只健康成年ESS犬。
从英国的一家综合诊所的犬群中前瞻性招募动物。对犬只进行两次检查，间隔至少12个月，以排除患有进行性心脏病的犬只。测量二尖瓣环平面收缩期位移、组织多普勒成像二尖瓣环速度以及二维斑点追踪超声心动图左心室纵向应变和应变率。检查了操作者内和观察者内的变异性，并计算了参考区间。研究了体重、年龄和心率对这些变量的潜在影响。
除组织多普勒成像E'（脉冲波多普勒测定的舒张早期二尖瓣环运动峰值速度）和二维斑点追踪超声心动图变量外，所有参数的操作者内和观察者内变异性均<10%，这些变量均<20%。39只犬用于建立参考区间。检测到年龄、心率和体重对……有显著（但大多较弱）影响。参考区间与先前在不同品种中发表的值相似。
给出了ESS左心室纵向功能测量的品种特异性参考区间。
