Saha Pradeep Kumar, Chakraborty Abhijit, Layek Avik Kumar, Chakraborty Aritra
Department of Psychiatry, Institute of Psychiatry, Kolkata, West Bengal, India.
Indian J Psychol Med. 2017 May-Jun;39(3):364-365. doi: 10.4103/0253-7176.207320.
Neuroleptic malignant syndrome (NMS) is a life-threatening adverse effect usually seen with typical antipsychotic drugs. Rarely, NMS can occur with atypical antipsychotics also. A 19-year-old male diagnosed as a case of acute and transient psychotic disorder developed NMS, following the treatment with an atypical antipsychotic, olanzapine 20 mg/day. The patient was diagnosed NMS, an offending agent olanzapine was immediately withdrawn, and prompt treatment by maintaining hydration and giving bromocriptine produced recovery.
抗精神病药恶性综合征(NMS)是一种危及生命的不良反应,通常见于典型抗精神病药物。非典型抗精神病药物也很少会引发NMS。一名19岁男性被诊断为急性短暂性精神病性障碍,在接受非典型抗精神病药物奥氮平20毫克/天治疗后出现了NMS。该患者被诊断为NMS,立即停用了致病药物奥氮平,并通过维持水合作用和给予溴隐亭进行及时治疗,患者最终康复。