重症新型冠状病毒肺炎中的恶性高热：2例病例报告

Malignant hyperthermia in severe COVID-19: 2 case reports.

作者信息

Ehteshami-Afshar Solmaz, Nikooie Roozbeh, Reddy Pranav, Chichra Astha, Siegel Mark D

机构信息

Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.

出版信息

Emerg Crit Care Med. 2021 Sep 15;1(1):45-48. doi: 10.1097/EC9.0000000000000013. eCollection 2021 Sep.

DOI:10.1097/EC9.0000000000000013

PMID:38630110

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8447731/

Abstract

Malignant hyperthermia is a rare but potentially fatal condition. We present 2 cases of young patients with coronavirus disease 2019 (COVID-19) requiring intubation for hypoxic respiratory failure who both developed significant hyperthermia post intubation and were suspected to have malignant hyperthermia. However, the 2 patients had different responses to conservative management and dantrolene. These cases highlight the increased challenge imposed by intubation complications when managing patients with COVID-19.

摘要

恶性高热是一种罕见但可能致命的疾病。我们报告了2例2019冠状病毒病（COVID-19）的年轻患者，他们因低氧性呼吸衰竭需要插管，插管后均出现明显高热，并被怀疑患有恶性高热。然而，这2例患者对保守治疗和丹曲林的反应不同。这些病例凸显了在管理COVID-19患者时插管并发症带来的更大挑战。