Mamut Adiel, Carlson Kevin V
Section of Urology, Department of Surgery, University of Calgary, Calgary, AB, Canada.
Can Urol Assoc J. 2017 Jun;11(6Suppl2):S152-S154. doi: 10.5489/cuaj.4612.
Urethral bulking aims to improve urethral mucosal coaptation, and thus outlet resistance, in an effort to limit stress-induced leakage. While efforts have been made to employ bulking agents to treat stress urinary incontinence (SUI) for more than 100 years, we remain wanting for the perfect injectable. Regardless of the agent studied, efficacy is modest at best, repeat injections are the norm, and long-term followup is conspicuously lacking. This treatment, however, fills an important need in our armamentarium against SUI, serving those patients who are not candidates for more invasive interventions and those with multiple prior failed surgeries. This review offers a contemporary discussion on the role of periurethral bulking therapy in Canada, along with practical aspects of its application.
尿道填充旨在改善尿道黏膜贴合，从而增加出口阻力，以限制压力性漏尿。尽管使用填充剂治疗压力性尿失禁（SUI）已有100多年的历史，但我们仍在寻找理想的可注射材料。无论研究何种材料，其疗效充其量只能说是一般，重复注射很常见，而且明显缺乏长期随访。然而，这种治疗方法满足了我们对抗SUI的重要需求，为那些不适合更具侵入性干预措施的患者以及之前多次手术失败的患者提供了帮助。本文综述了加拿大围尿道填充治疗的作用，并探讨了其实际应用方面的问题。
