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胃肠道腺癌的皮肤表现。

Cutaneous presentation of gastrointestinal adenocarcinoma.

作者信息

Halder Aditi, Tatian Artiene, Vargas A Cristina, Karim Rooshdiya, Latt Mark

机构信息

Department of Geriatrics, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia.

Department of Surgical Oncology, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia.

出版信息

J Surg Case Rep. 2017 Jun 7;2017(6):rjx083. doi: 10.1093/jscr/rjx083. eCollection 2017 Jun.

DOI:10.1093/jscr/rjx083
PMID:28616154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5461471/
Abstract

Seeding of a central nervous system malignancy to the abdominal cavity is an uncommon but well documented complication of a ventriculoperitoneal (VP) shunt. However, the metastasis of a primary gastrointestinal cancer to the skin via a VP shunt is extremely rare. We report the clinical case of an 85-year-old male who presented with a right upper quadrant nodule over his shunt, which on histopathology and tumour marker profile was diagnosed as an adenocarcinoma of likely upper gastrointestinal origin. This case illustrates the importance of proceeding to biopsy to inform prognosis and management, despite the risks of shunt infection.

摘要

中枢神经系统恶性肿瘤播散至腹腔是脑室腹腔(VP)分流术一种虽不常见但有充分文献记载的并发症。然而,原发性胃肠道癌经VP分流术转移至皮肤极为罕见。我们报告一例85岁男性的临床病例,该患者分流管处出现右上腹结节,经组织病理学和肿瘤标志物检查,诊断为可能起源于上消化道的腺癌。该病例说明,尽管存在分流管感染风险,但进行活检以指导预后和治疗仍很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/6ace6da0b572/rjx083f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/f9a15caf3211/rjx083f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/c847467948f4/rjx083f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/6ace6da0b572/rjx083f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/f9a15caf3211/rjx083f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/c847467948f4/rjx083f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb3e/5461471/6ace6da0b572/rjx083f03.jpg

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本文引用的文献

1
A case of breast cancer involving a ventriculoperitoneal shunt.一例累及脑室腹腔分流管的乳腺癌病例。
Surg Case Rep. 2016 Dec;2(1):8. doi: 10.1186/s40792-016-0136-7. Epub 2016 Feb 6.
2
Metastasis of primary CNS lymphoma along a ventriculoperitoneal shunt.
J Clin Oncol. 2011 Dec 1;29(34):e823-4. doi: 10.1200/JCO.2011.37.3233. Epub 2011 Oct 24.
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Shunt-related abdominal metastases in a child with choroid plexus carcinoma: case report.
Neurosurgery. 2005 Feb;56(2):E412; discussion E412. doi: 10.1227/01.neu.0000147982.80732.3d.
4
Subcutaneous seeding of pancreatic carcinoma along a VP shunt catheter.
Lancet Oncol. 2002 Nov;3(11):683. doi: 10.1016/s1470-2045(02)00904-x.