Spirig José M, Frank Melanie N, Regli Luca, Stieglitz Lennart H
Department of Neurosurgery, University of Zurich and University Hospital Zurich, 8091, Zurich, Switzerland.
Faculty of Medicine, University of Zürich, Zürich, Switzerland.
Acta Neurochir (Wien). 2017 Aug;159(8):1421-1428. doi: 10.1007/s00701-017-3237-6. Epub 2017 Jun 14.
Patients admitted for suspicion of shunt dysfunction (SD) often show unspecific symptoms and require time-consuming, expensive and even invasive diagnostics involving significant radiation exposure. The purpose of this retrospective study was to analyse the current diagnostic procedures and to propose a process optimisation.
As all patients admitted for suspicion of SD receive imaging studies, we searched for adult patients receiving neuroimaging in the period from January 2010 to July 2013, analysing referring diagnosis, clinical signs, products, diagnostic process and final diagnosis. Recursive partitioning was used to define time intervals for differentiating types of SD.
A total of 148 patients, aged 18-89 (mean, 54) years, were studied. Forty-two percent were referred by a hospital or rehabilitation centre, 30% by general practitioners and 24% were self-referrals. The admission diagnosis was in the majority "shunt dysfunction" only. Further differentiations were rarely made. An SD was confirmed in 46% of the patients. In 17%, the symptoms were based on another cause and in 37% they could not be clearly attributed to any specific disorder. Abdominal dislocations (2%) and shunt infections (5%) were found within the first 6 months. Over- (3%) and under-drainage (14%) were the most frequent complications during the first 4 years. Disconnections (13%) occurred generally 4 years or more after implantation. Only shunt obstruction (9%) showed no temporal pattern.
Symptoms of SD remain mostly unspecific. This study showed that the type of SD depends on the time interval from implantation. We propose a workup strategy for patients with SD based on the temporal profile.
因怀疑分流功能障碍(SD)而入院的患者通常表现出非特异性症状,需要耗时、昂贵甚至侵入性的诊断,且涉及大量辐射暴露。这项回顾性研究的目的是分析当前的诊断程序并提出流程优化建议。
由于所有因怀疑SD而入院的患者均接受影像学检查,我们搜索了2010年1月至2013年7月期间接受神经影像学检查的成年患者,分析转诊诊断、临床体征、检查项目、诊断流程及最终诊断。采用递归划分法定义区分SD类型的时间间隔。
共研究了148例年龄在18 - 89岁(平均54岁)的患者。42%由医院或康复中心转诊,30%由全科医生转诊,24%为自我转诊。入院诊断大多仅为“分流功能障碍”。很少进行进一步区分。46%的患者确诊为SD。17%的患者症状由其他原因引起,37%的患者症状无法明确归因于任何特定疾病。在最初6个月内发现腹部移位(2%)和分流感染(5%)。在前4年中,过度引流(3%)和引流不足(14%)是最常见的并发症。断开连接(13%)通常发生在植入后4年或更久。只有分流梗阻(9%)没有时间模式。
SD的症状大多仍不具有特异性。本研究表明,SD的类型取决于植入后的时间间隔。我们基于时间特征为SD患者提出了一种检查策略。