Li Wei-Min, Zhao Shuang, Liu Lun-Xu
Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 61004, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2017 May;48(3):331-335.
Lung cancer is the leading contributor to morbidity and mortality from cancer worldwide, with its 5-year overall survival being only about 15.6%. Due to the lack of specific early screening methods for lung cancer, about 75% patients are diagnosed late. Therefore, it remains the big challenge for the early diagnosis of lung cancer. We need to pay more attention to the screening of lung cancer, and more precise assessment and management to the pulmonary nodules screened out. Further study on liquid biopsy, optimization of new fiberoptic bronchoscopy and the sampling methods to harvest small volume of lung tissue, could be helpful to improve the early diagnosis of lung cancer.
肺癌是全球癌症发病率和死亡率的主要贡献因素,其5年总生存率仅约为15.6%。由于缺乏针对肺癌的特异性早期筛查方法,约75%的患者被诊断为晚期。因此,肺癌的早期诊断仍然是一个巨大的挑战。我们需要更加关注肺癌的筛查,以及对筛查出的肺结节进行更精确的评估和管理。对液体活检进行进一步研究、优化新型纤维支气管镜及小体积肺组织获取的采样方法,可能有助于提高肺癌的早期诊断率。