Chaudhary B A, Yoneda K, Burki N K
J Thorac Cardiovasc Surg. 1978 Jul;76(1):33-7.
We have compared the relative value of various techniques used in association with fiberoptic bronchoscopy for the diagnosis of lung cancer. We analyzed the results in 114 patients who underwent diagnostic fiberoptic bronchoscopy and in whom a definite histologic diagnosis of lung cancer was made. A comparison of the diagnostic yield from cytologic examination of prebronchoscopy and postbronchoscopy sputum and of fiberoptic bronchial biopsy, brushing, and washing was made. Over-all, bronchial washings gave the highest diagnostic yield (75.4%) and forceps biopsy the next higher (65.8%). The combination of bronchial washings and forceps biopsy gave the highest diagnostic yield (95.8%). In six patients, postbronchoscopy sputum was the only source of positive diagnostis; in 20 patients only one procedure was positive. Our results suggest that although fiberoptic bronchoscopy washings and forceps biopsy have the highest diagnostic yield, brushings and postbronchoscopic sputum examination are also important diagnostic maneuvers and should be routinely performed.
我们比较了与纤维支气管镜检查联合使用的各种技术在肺癌诊断中的相对价值。我们分析了114例行诊断性纤维支气管镜检查且最终确诊为肺癌患者的结果。对支气管镜检查前和检查后痰液的细胞学检查以及纤维支气管活检、刷检和灌洗的诊断阳性率进行了比较。总体而言，支气管灌洗的诊断阳性率最高（75.4%），钳取活检次之（65.8%）。支气管灌洗和钳取活检相结合的诊断阳性率最高（95.8%）。在6例患者中，支气管镜检查后的痰液是唯一的阳性诊断来源；在20例患者中，只有一种检查方法呈阳性。我们的结果表明，虽然纤维支气管镜灌洗和钳取活检的诊断阳性率最高，但刷检和支气管镜检查后的痰液检查也是重要的诊断手段，应常规进行。
