Zito J M, Routt W W, Mitchell J E, Roerig J L
Am J Psychiatry. 1985 Jul;142(7):822-6. doi: 10.1176/ajp.142.7.822.
Thirty psychotic patients who refused antipsychotic medication were compared with 30 patients matched for age, sex, treatment ward, commitment status, and diagnosis who consented to drug treatment. Refusers were no more assaultive or combative than consenters; they were less often diagnosed as having schizophrenia and more often diagnosed as having bipolar or schizoaffective illness. A comparison between 17 of the least symptomatic refusers and 17 of the most persistent refusers showed that persistent refusers were more likely to have a diagnosis of schizophrenia; least symptomatic refusers were more often diagnosed as having affective disorders or schizoaffective disorders.
将30名拒绝服用抗精神病药物的精神病患者与30名在年龄、性别、治疗病房、住院状态和诊断方面相匹配且同意接受药物治疗的患者进行比较。拒绝服药者并不比同意服药者更具攻击性或好斗性；他们被诊断为精神分裂症的频率较低，而被诊断为双相情感障碍或分裂情感性障碍的频率较高。对17名症状最轻的拒绝服药者和17名最顽固的拒绝服药者进行比较发现，顽固的拒绝服药者更有可能被诊断为精神分裂症；症状最轻的拒绝服药者更常被诊断为情感障碍或分裂情感性障碍。
