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一种用于植入可长期硬膜外给予阿片类药物以治疗癌痛的门静脉系统的技术。

A technique for the insertion of an implantable portal system for the long-term epidural administration of opioids in the treatment of cancer pain.

作者信息

Cherry D A, Gourlay G K, Cousins M J, Gannon B J

出版信息

Anaesth Intensive Care. 1985 May;13(2):145-52. doi: 10.1177/0310057X8501300206.

Abstract

The feasibility of using a subcutaneously implanted portal system attached to a conventional 16-gauge epidural catheter has been evaluated in 50 patients with sever pain associated with cancer. This technique allowed for the percutaneous epidural administration of morphine at 8-12-hourly intervals for pain control. The mean duration of implantation was 12 weeks and the longest period a portal remained in situ was 36 weeks. Five portals had to be removed for various reasons. The injection system has blocked on eight occasions due to catheter blockage (six times) and portal blockage (two occasions). These patients have continued to obtain excellent analgesia when either catheter or portal were replaced. In a cadaver, 300 injections were simulated using either 22-gauge Huber point needles or disposable needles (25 gauge) and the injectate examined by both light and scanning electron microscopy. Both needle types resulted in particulate contamination which was greater with the recommended Huber point needles.

摘要

在50例患有严重癌痛的患者中,评估了使用连接传统16号硬膜外导管的皮下植入式门体系统的可行性。该技术允许每8至12小时经皮硬膜外注射吗啡以控制疼痛。平均植入持续时间为12周,门体系统在位最长时间为36周。因各种原因有5个门体系统被移除。注射系统因导管堵塞(6次)和门体系统堵塞(2次)曾8次出现阻塞情况。当更换导管或门体系统时,这些患者仍能持续获得良好的镇痛效果。在一具尸体上,使用22号休伯点针或一次性针(25号)模拟进行了300次注射,并通过光学显微镜和扫描电子显微镜对注射剂进行了检查。两种类型的针均导致了微粒污染,推荐使用的休伯点针造成的污染更严重。

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