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[腹膜后及胰腺黏液性肿瘤。免疫组织化学研究]

[Retroperitoneal and pancreatic mucinous tumors. Immunohistochemical study].

作者信息

Fetissof F, Dubois M P, Legue E, de Calan L, Jobard P

出版信息

Ann Pathol. 1985;5(1):53-7.

PMID:2861827
Abstract

Examples of mucinous tumors from retroperitoneum (2) and pancreas (1) were studied. These tumors share many morphological similarities with ovarian mucinous tumour and adenoma malignum of uterine cervix. They have a similar spectrum of endocrine cells; serotonin, somatostatin, gastrin and pancreatic polypeptide cells were characterized. In nonproliferative areas was found a well-differentiated mucinous columnar epithelium with scarce endocrine cell. In more proliferative areas were found either a mucinous columnar lining with infolds and secondary glands or a less well-differentiated intestinal-type epithelium with papillary formations; both linings were well supplied in endocrine cells.

摘要

对来自腹膜后(2例)和胰腺(1例)的黏液性肿瘤进行了研究。这些肿瘤在形态学上与卵巢黏液性肿瘤和子宫颈恶性腺瘤有许多相似之处。它们具有相似的内分泌细胞谱;对血清素、生长抑素、胃泌素和胰多肽细胞进行了表征。在非增殖区域发现了分化良好的黏液柱状上皮,内分泌细胞稀少。在增殖较多的区域,发现了有褶皱和次级腺体的黏液柱状内衬,或有乳头形成的分化较差的肠型上皮;两种内衬的内分泌细胞都很丰富。

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