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复发性嵌甲感染后拇趾的马乔林鳞状细胞癌

Marjolin's squamous cell carcinoma of the hallux following recurrent ingrown toenail infections.

作者信息

Abdul Wahid, O'Neill Barry James, Perera Anthony

机构信息

Department of Trauma and Orthopaedics, University Hospital of Wales, Cardiff, UK.

出版信息

BMJ Case Rep. 2017 Jun 14;2017:bcr-2017-219715. doi: 10.1136/bcr-2017-219715.

Abstract

Marjolin's squamous cell carcinoma (SCC) affecting the toe is rare. Due to resemblance with benign conditions it can often result in misdiagnosis. We report a case of Marjolin's SCC affecting the proximal hallux in a patient with recurrent ingrown toenail infections. A 58-year-old woman with a background of wedge resections for ingrown toenail and distal phalanx amputation for osteomyelitis presented with pain and hyperkeratotic raised ulcer around the proximal phalanx. MRI scan revealed soft tissue mass infiltrating the proximal phalanx with biopsies confirming a SCC. The patient underwent first ray amputation and made a good clinical recovery and remains disease free. Due to clinical similarities with benign conditions, awareness of Marjolin's SCC as a potential diagnosis when treating patients with recurrent ingrown toenail is imperative. We recommend patients with recurrent ingrown toenail or ulceration with a background of chronic infection have biopsies performed to exclude potential malignancy.

摘要

累及脚趾的马乔林溃疡型鳞状细胞癌(SCC)很罕见。由于其与良性疾病相似,常常会导致误诊。我们报告一例马乔林溃疡型SCC累及一名复发性嵌甲感染患者的拇趾近节趾骨。一名58岁女性,有因嵌甲行楔形切除术及因骨髓炎行远节趾骨截肢术病史,现因近节趾骨周围疼痛及角化过度性隆起溃疡就诊。磁共振成像(MRI)扫描显示软组织肿块浸润近节趾骨,活检证实为鳞状细胞癌。患者接受了第一跖骨截肢术,临床恢复良好,且无疾病复发。由于与良性疾病在临床上有相似之处,在治疗复发性嵌甲患者时,必须意识到马乔林溃疡型SCC作为一种潜在诊断的可能性。我们建议有复发性嵌甲或有慢性感染背景的溃疡患者进行活检以排除潜在恶性肿瘤。

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本文引用的文献

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Marjolin's ulcer of the hallux.拇趾马乔林溃疡
J Am Podiatr Med Assoc. 2013 May-Jun;103(3):250-3. doi: 10.7547/1030250.
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Primary squamous cell carcinoma of the distal hallux.拇趾远节原发性鳞状细胞癌
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Marjolin's ulcer: modern analysis of an ancient problem.马乔林溃疡:对一个古老问题的现代分析
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