Pier Bruce D, Bates G Wright
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, The University of Alabama at Birmingham, WIC 10390, 1700 6th Avenue South, Birmingham, AL 35294 UK.
Fertil Res Pract. 2015 Aug 25;1:12. doi: 10.1186/s40738-015-0005-2. eCollection 2015.
Intramural leiomyomas have been long debated as a potential cause of infertility and pregnancy loss.
Previous research has linked intramural fibroids to defective implantation, as well as to abnormal peristaltic events of the uterine smooth muscle. Previous reports describe the effects of intramural fibroids on normal human fertility and early pregnancy loss, specifically in regards to implantation failure.
A thorough understanding of prior research may direct new research focus, leading to better understanding of leiomyoma-associated infertility.
壁间平滑肌瘤一直被视为不孕症和流产的潜在原因,备受争议。
先前的研究已将壁间肌瘤与植入缺陷以及子宫平滑肌异常蠕动事件联系起来。先前的报告描述了壁间肌瘤对正常人类生育能力和早期流产的影响,特别是在植入失败方面。
对先前研究的透彻理解可能会引导新的研究重点,从而更好地理解与平滑肌瘤相关的不孕症。