Anderson Daniel A, Tretiakova Maria S
Department of Pathology, UWMC Anatomic Pathology, University of Washington, 1959 NE Pacific St., P.O. Box 356100, Seattle, WA 98195-6100, USA.
Department of Pathology, University of Washington, 325 Ninth Avenue, P.O. Box 359791, Seattle, WA 98104, USA.
Case Rep Pathol. 2017;2017:9672368. doi: 10.1155/2017/9672368. Epub 2017 May 23.
Clear cell papillary renal cell carcinoma (CCPRCC) is a newly recognized entity in the 2016 WHO classification and usually presents as a small, circumscribed, solitary mass of indolent nature. CCPRCCs could seldom occur in conjunction with other synchronous or metachronous kidney tumors and even less frequently as bilateral masses. To our knowledge, multiple bilateral CCPRCCs have never been described with the existence of a synchronous well-differentiated neuroendocrine tumor of the kidney and hence reported here as a unique case. This case report highlights the importance in considering this entity and its unusual presentation in the differential diagnosis as a possible mimicker of Von Hippel-Lindau syndrome.
透明细胞乳头状肾细胞癌（CCPRCC）是2016年世界卫生组织分类中 newly recognized entity，通常表现为一个小的、边界清楚的、孤立的、惰性的肿块。CCPRCC很少与其他同时性或异时性肾肿瘤同时发生，更罕见的是双侧肿块。据我们所知，从未有过关于双侧多发CCPRCC合并同时性肾高分化神经内分泌肿瘤的报道，因此在此报告这一独特病例。本病例报告强调了在鉴别诊断中考虑这一实体及其不寻常表现的重要性，因为它可能是冯·希佩尔-林道综合征的一种可能的模仿者。
