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自发性高血压大鼠肾上腺髓质中酪氨酸羟化酶的定量免疫荧光分析

Quantitative immunofluorescence of tyrosine hydroxylase in the adrenal medulla of spontaneously hypertensive rats.

作者信息

Nagatsu I, Ito M, Kawakami Y, Karasawa N, Takahashi H, Fujita K, Nagatsu T

出版信息

Experientia. 1985 Aug 15;41(8):1054-5. doi: 10.1007/BF01952140.

DOI:10.1007/BF01952140
PMID:2862059
Abstract

The amount of tyrosine hydroxylase protein in the adrenal medulla, which was estimated by a quantitative immunofluorescence method, was higher in spontaneously hypertensive rats than in normotensive control Wistar-Kyoto rats at 4 and 16 weeks of age before and after the development of hypertension.

摘要

采用定量免疫荧光法估算,在高血压发生之前及之后的4周龄和16周龄时,自发性高血压大鼠肾上腺髓质中酪氨酸羟化酶蛋白的含量高于正常血压对照Wistar-Kyoto大鼠。

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Quantitative immunofluorescence of tyrosine hydroxylase in the adrenal medulla of spontaneously hypertensive rats.自发性高血压大鼠肾上腺髓质中酪氨酸羟化酶的定量免疫荧光分析
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本文引用的文献

1
Development of a strain of spontaneously hypertensive rats.一种自发性高血压大鼠品系的培育
Jpn Circ J. 1963 Mar;27:282-93. doi: 10.1253/jcj.27.282.
2
A new methodological approach for studying axonal transport: cytofluorometric scanning of nerves.一种研究轴突运输的新方法:神经细胞荧光扫描法。
J Histochem Cytochem. 1984 Jan;32(1):7-16. doi: 10.1177/32.1.6197439.
3
Detection of inactive or less active forms of tyrosine hydroxylase in human adrenals by a sandwich enzyme immunoassay.采用夹心酶免疫测定法检测人肾上腺中酪氨酸羟化酶的无活性或活性较低的形式。
Anal Biochem. 1984 Apr;138(1):125-32. doi: 10.1016/0003-2697(84)90779-6.
4
A new approach to quantitate the density and antigen contents of high densities of transmitter-identified terminals. Immunocytochemical studies on different types of tyrosine hydroxylase immunoreactive nerve terminals in nucleus caudatus putamen of the rat.一种定量高密度递质识别终末密度和抗原含量的新方法。对大鼠尾状核壳核中不同类型酪氨酸羟化酶免疫反应性神经终末的免疫细胞化学研究。
Neurosci Lett. 1982 Oct 23;32(3):253-8. doi: 10.1016/0304-3940(82)90302-0.
5
An improved microfluorimeter for measuring brightness of fluorescent antibody reactions.
J Histochem Cytochem. 1967 Jan;15(1):38-45. doi: 10.1177/15.1.38.
6
Adrenal tyrosine hydroxylase and dopamine beta-hydroxylase in spontaneously hypertensive rats.
Nature. 1971 Apr 9;230(5293):381-2. doi: 10.1038/230381a0.
7
Letter: Sympathoadrenal medullary activity in young, spontaneously hypertensive rats.信函:年轻自发性高血压大鼠的交感肾上腺髓质活动
Nature. 1975 Nov 20;258(5532):267-8. doi: 10.1038/258267a0.
8
Retrograde axoplasmic transport to inactive dopamine beta-hydroxylase in sciatic nerves.坐骨神经中逆行轴浆运输至无活性多巴胺β-羟化酶
Brain Res. 1976 Nov 5;116(2):277-85. doi: 10.1016/0006-8993(76)90905-7.